A paired-agent fluorescence tomography method to detect and localize cancer burden in excised lymph nodes

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Abstract

This work presents a method to detect and localize cancer burden in surgically excised lymph nodes from head and neck cancer patients. Results from porcine lymph nodes implanted with human head and neck cancer spheroids demonstrate that cancer cell clusters as small as 100-microns can be detected with >99% sensitivity and specificity within 30 min.

Original languageEnglish
Title of host publicationOptica Biophotonics Congress 2025
PublisherOptica Publishing Group
ISBN (Electronic)978-1-957171-46-3
DOIs
Publication statusPublished - 2025
Event2025 Optical Molecular Probes, Imaging and Drug Delivery, OMP 2025 - Coronado, United States
Duration: 21-Apr-202524-Apr-2025

Publication series

NameOptica Biophotonics Congress: Optics in the Life Sciences
PublisherOptica Publishing Group

Conference

Conference2025 Optical Molecular Probes, Imaging and Drug Delivery, OMP 2025
Country/TerritoryUnited States
CityCoronado
Period21/04/202524/04/2025

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