A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter

M Kleerebezem, OP Kuipers, WM de Vos, ME Stiles, LEN Quadri*, Willem M. de Vos, Michael E. Stiles, Luis E.N. Quadri

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

In the lactic acid bacterium Carnobacterium piscicola LV17B a peptide-pheromone dependent quorum-sensing mode is involved in the regulation of bacteriocin production. Bacteriocin CB2 was identified as an environmental signal that induces bacteriocin production. Here, we demonstrate that a second 24 amino acid peptide (CS) also induces bacteriocin production. Transcription activation of several carnobacteriocin operons is triggered by CB2 or CS via a two-component signal transduction system composed of CbnK and CbnR. (C) 2001 Elsevier Science Inc. All rights reserved.

Original languageEnglish
Pages (from-to)1597-1601
Number of pages5
JournalPeptides
Volume22
Issue number10
DOIs
Publication statusPublished - Oct-2001

Keywords

  • bacteriocin
  • signal transduction
  • peptide pheromone
  • regulation
  • quorum sensing
  • LACTOBACILLUS-PLANTARUM C-11
  • GRAM-POSITIVE BACTERIA
  • IMMUNITY
  • PROTEIN
  • LOCUS
  • OSMOREGULATION
  • LACTOCOCCUS
  • EXPRESSION
  • INDUCTION
  • SYSTEMS

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