TY - JOUR
T1 - Abnormal Fetal Growth
T2 - Small for Gestational Age, Fetal Growth Restriction, Large for Gestational Age: Definitions and Epidemiology
AU - Damhuis, Stefanie E
AU - Ganzevoort, Wessel
AU - Gordijn, Sanne J
N1 - Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.
PY - 2021/6
Y1 - 2021/6
N2 - Abnormal fetal growth (growth restriction and overgrowth) is associated with perinatal morbidity, mortality, and lifelong risks to health. To describe abnormal growth, "small for gestational age" and "large for gestational age" are commonly used terms. However, both are statistical definitions of fetal size below or above a certain threshold related to a reference population, rather than referring to an abnormal condition. Fetuses can be constitutionally small or large and thus healthy, whereas fetuses with seemingly normal size can be growth restricted or overgrown. Although golden standards to detect abnormal growth are lacking, understanding of both pathologic conditions has improved significantly.
AB - Abnormal fetal growth (growth restriction and overgrowth) is associated with perinatal morbidity, mortality, and lifelong risks to health. To describe abnormal growth, "small for gestational age" and "large for gestational age" are commonly used terms. However, both are statistical definitions of fetal size below or above a certain threshold related to a reference population, rather than referring to an abnormal condition. Fetuses can be constitutionally small or large and thus healthy, whereas fetuses with seemingly normal size can be growth restricted or overgrown. Although golden standards to detect abnormal growth are lacking, understanding of both pathologic conditions has improved significantly.
U2 - 10.1016/j.ogc.2021.02.002
DO - 10.1016/j.ogc.2021.02.002
M3 - Review article
C2 - 33972065
SN - 0889-8545
VL - 48
SP - 267
EP - 279
JO - Obstetrics and gynecology clinics of North America
JF - Obstetrics and gynecology clinics of North America
IS - 2
ER -