Abnormal glomerular basement membrane in idiopathic multicentric osteolysis

SJL Bakker, GD Vos, PDMM Verschure, AH Mulder, TMG Tiebosch

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The primary cause of nephropathy in idiopathic multicentric osteolysis is as yet unknown. We report a young girl with idiopathic multicentric osteolysis and nephropathy. An abnormal glomerular basement membrane was the only abnormality found in a renal biopsy taken 2 years before the development of end-stage renal failure. We believe that this biopsy finding represents or is related to the unknown primary lesion causing nephropathy in idiopathic multicentric osteolysis.

Original languageEnglish
Pages (from-to)200-202
Number of pages3
JournalPediatric Nephrology
Issue number2
Publication statusPublished - Apr-1996


  • idiopathic multicentric osteolysis
  • nephropathy
  • glomerular basement membrane
  • nail-patella syndrome
  • end-stage renal failure

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