Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases

  • R.de Pril
  • , D.F. Fischer
  • , M.L.C. Maat-Schieman
  • , B. Hobo
  • , R.A.I.de Vos
  • , E.R. Brunt
  • , E.M. Hol
  • , R.A.C. Roos
  • , F.W.van Leeuwen

    Research output: Contribution to journalArticleAcademicpeer-review

    94 Citations (Scopus)
    150 Downloads (Pure)
    Original languageEnglish
    Pages (from-to)1803-1813
    Number of pages11
    JournalHuman Molecular Genetics
    Volume13
    Issue number16
    DOIs
    Publication statusPublished - 2004

    Keywords

    • HUNTINGTONS-DISEASE
    • ALZHEIMERS-DISEASE
    • INTRANUCLEAR INCLUSIONS
    • EXPANDED POLYGLUTAMINE
    • PROTEASOME SYSTEM
    • MUTANT UBIQUITIN
    • DYSTROPHIC NEURITES
    • CALCIUM-CHANNEL
    • GENE-PRODUCT
    • PROTEIN

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