Activation of Epac2 improves Aβ-induced impairment of memory retrieval in an acute model of Alzheimer's disease

Keyphrases

• Memory Retrieval 100%
• Alzheimer's Disease Model 100%
• Acute Model 100%
• Exchange Protein Directly Activated by cAMP 100%
• Memory Impairment 60%
• Alzheimer's Disease 40%
• Impaired Memory 40%
• Spontaneous Excitatory Postsynaptic Current (sEPSC) 20%
• Memory Performance 20%
• Contextual Fear Conditioning 20%
• Neuronal Activity 20%
• CA1 Neurons 20%
• Intracellular Calcium 20%
• Potential Treatments 20%
• Targeted Treatment 20%
• Synaptic Memory 20%
• Firing Rate 20%
• Neuronal Firing 20%
• Action Potential 20%
• Enhancement Effect 20%
• Synaptic Communication 20%
• Synaptic Activity 20%
• Enhancing Memory 20%
• Intrahippocampal Injection 20%
• Primary Neuronal Culture 20%
• Activity Impairment 20%
• Cognitive Markers 20%

Neuroscience

• Alzheimer's Disease 100%
• Cyclic Adenosine Monophosphate 100%
• Antiporter 100%
• Memory Disorder 60%
• Fear Conditioning 20%
• Firing Rate 20%
• Action Potential 20%
• Oligomer 20%
• Amyloid Protein 20%