Adductor spasmodic dysphonia and botulinum toxin treatment: The effect on well-being

TPM Langeveld*, F Luteijn, M van Rossum, HA Drost, RJB De Jong

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    13 Citations (Scopus)


    Adductor spasmodic dysphonia (AdSD) is a controversial and enigmatic voice disorder. It is generally accepted that it has a neurologic, although undetermined, cause, and it is accompanied by much psychological and physical distress. In this prospective study, standardized psychometric tests were used to assess the personality characteristics and psychological and somatic well-being of 46 patients with AdSD. Moreover, the effect of botulinum toxin (Botox) treatment on their well-being was evaluated. No significant differences could be detected between patients and a representative norm group concerning 7 personality characteristics. Nevertheless, before treatment, there were significantly more psychological and somatic complaints. After establishment of a normal to near-normal voice with Botox injections, these complaints were reduced to normal levels - a finding suggesting these phenomena to be secondary to the voice disorder. These findings, and the normal personality characteristics, do not support a psychogenic cause of AdSD.

    Original languageEnglish
    Pages (from-to)941-945
    Number of pages5
    JournalAnnals of otology rhinology and laryngology
    Issue number10
    Publication statusPublished - Oct-2001


    • adductor spasmodic dysphonia
    • botulinum toxin
    • psychometry

    Cite this