Adolescent social defeat disturbs adult aggression-related impulsivity in wild-type rats

Caroline M. Coppens*, Alex Coolen, Sietse F. de Boer, Jaap M. Koolhaas

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Abstract

Adolescence is generally considered as a developmental period during which adverse social experiences may have lasting consequences in terms of an increased vulnerability to affective disorders. This study aimed at determining the individual susceptibility to adolescent social stress using a rat model.

We used rats of the Wild-type Groningen strain, which are characterized by a broad variation in adult levels of aggression and impulsivity. We hypothesized that experience of social defeat in adolescence results in heightened aggression and impulsivity levels in adulthood.

In contrast to our expectation, adolescent social defeat did not lead to a difference in the average adult level of aggression and impulsivity, but the significant correlation between offensive aggression and impulsivity found in control animals was not present in animals defeated during adolescence. (C) 2014 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)191-196
Number of pages6
JournalBehavioural Processes
Volume108
DOIs
Publication statusPublished - Oct-2014

Keywords

  • Adolescence
  • Social defeat
  • Aggression
  • Impulsivity
  • Coping style
  • MALE GOLDEN-HAMSTERS
  • INDIVIDUAL-DIFFERENCES
  • COPING STYLES
  • BRAIN-DEVELOPMENT
  • STRESS RESPONSES
  • AVOIDANCE RATS
  • BEHAVIOR
  • VICTIMIZATION
  • VULNERABILITY
  • DEPRESSION

Cite this