Age of Onset and Lifetime Projected Risk of Psychotic Experiences: Cross-National Data From the World Mental Health Survey

John J. McGrath; Sukanta Saha; Ali O. Al-Hamzawi; Jordi Alonso; Laura Andrade; Guilherme Borges; Evelyn J. Bromet; Mark Oakley Browne; Ronny Bruffaerts; Jose M. Caldas de Almeida; John Fayyad; Silvia Florescu; Giovanni de Girolamo; Oye Gureje; Chiyi Hu; Peter de Jonge; Viviane Kovess-Masfety; Jean Pierre Lepine; Carmen C. W. Lim; Fernando Navarro-Mateu; Maria Piazza; Nancy Sampson; Jose Posada-Villa; Kenneth S. Kendler; Ronald C. Kessler

doi:10.1093/schbul/sbw011

Age of Onset and Lifetime Projected Risk of Psychotic Experiences: Cross-National Data From the World Mental Health Survey

John J. McGrath^*, Sukanta Saha, Ali O. Al-Hamzawi, Jordi Alonso, Laura Andrade, Guilherme Borges, Evelyn J. Bromet, Mark Oakley Browne, Ronny Bruffaerts, Jose M. Caldas de Almeida, John Fayyad, Silvia Florescu, Giovanni de Girolamo, Oye Gureje, Chiyi Hu, Peter de Jonge, Viviane Kovess-Masfety, Jean Pierre Lepine, Carmen C. W. Lim, Fernando Navarro-MateuMaria Piazza, Nancy Sampson, Jose Posada-Villa, Kenneth S. Kendler, Ronald C. Kessler

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

72 Citations (Scopus)

Abstract

Background: Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features. Methods: Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime prevalence of PE. Projected lifetime risk (at age 75 years) was estimated using a 2-part actuarial method. AOO distributions were described for the observed and projected estimates. We examined associations of AOO with PE type metric and annualized PE frequency. Results: Projected lifetime risk for PEs was 7.8% (SE = 0.3), slightly higher than lifetime prevalence (5.8%, SE = 0.2). The median (interquartile range; IQR) AOO based on projected lifetime estimates was 26 (17-41) years, indicating that PEs commence across a wide age range. The AOO distributions for PEs did not differ by sex. Early AOO was positively associated with number of PE types (F = 14.1, P

Original language	English
Pages (from-to)	933-941
Number of pages	9
Journal	Schizophrenia Bulletin
Volume	42
Issue number	4
DOIs	https://doi.org/10.1093/schbul/sbw011
Publication status	Published - Jul-2016

Keywords

epidemiology
psychotic experiences
age of onset
lifetime prevalence
World Mental Health Survey
DELUSIONAL-LIKE EXPERIENCES
POPULATION-BASED SURVEY
GENERAL-POPULATION
DISORDERS
SYMPTOMS
SCHIZOPHRENIA
ASSOCIATION
ADULTS

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Age of Onset and Lifetime Projected Risk of Psychotic Experiences
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McGrath, J. J., Saha, S., Al-Hamzawi, A. O., Alonso, J., Andrade, L., Borges, G., Bromet, E. J., Browne, M. O., Bruffaerts, R., Caldas de Almeida, J. M., Fayyad, J., Florescu, S., de Girolamo, G., Gureje, O., Hu, C., de Jonge, P., Kovess-Masfety, V., Lepine, J. P., Lim, C. C. W., ... Kessler, R. C. (2016). Age of Onset and Lifetime Projected Risk of Psychotic Experiences: Cross-National Data From the World Mental Health Survey. Schizophrenia Bulletin, 42(4), 933-941. https://doi.org/10.1093/schbul/sbw011

@article{3b54cce0773b49dca51e1dda1c390ff5,

title = "Age of Onset and Lifetime Projected Risk of Psychotic Experiences: Cross-National Data From the World Mental Health Survey",

abstract = "Background: Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features. Methods: Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime prevalence of PE. Projected lifetime risk (at age 75 years) was estimated using a 2-part actuarial method. AOO distributions were described for the observed and projected estimates. We examined associations of AOO with PE type metric and annualized PE frequency. Results: Projected lifetime risk for PEs was 7.8% (SE = 0.3), slightly higher than lifetime prevalence (5.8%, SE = 0.2). The median (interquartile range; IQR) AOO based on projected lifetime estimates was 26 (17-41) years, indicating that PEs commence across a wide age range. The AOO distributions for PEs did not differ by sex. Early AOO was positively associated with number of PE types (F = 14.1, P",

keywords = "epidemiology, psychotic experiences, age of onset, lifetime prevalence, World Mental Health Survey, DELUSIONAL-LIKE EXPERIENCES, POPULATION-BASED SURVEY, GENERAL-POPULATION, DISORDERS, SYMPTOMS, SCHIZOPHRENIA, ASSOCIATION, ADULTS",

author = "McGrath, {John J.} and Sukanta Saha and Al-Hamzawi, {Ali O.} and Jordi Alonso and Laura Andrade and Guilherme Borges and Bromet, {Evelyn J.} and Browne, {Mark Oakley} and Ronny Bruffaerts and {Caldas de Almeida}, {Jose M.} and John Fayyad and Silvia Florescu and {de Girolamo}, Giovanni and Oye Gureje and Chiyi Hu and {de Jonge}, Peter and Viviane Kovess-Masfety and Lepine, {Jean Pierre} and Lim, {Carmen C. W.} and Fernando Navarro-Mateu and Maria Piazza and Nancy Sampson and Jose Posada-Villa and Kendler, {Kenneth S.} and Kessler, {Ronald C.}",

note = "{\textcopyright} The Author 2016. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.",

year = "2016",

month = jul,

doi = "10.1093/schbul/sbw011",

language = "English",

volume = "42",

pages = "933--941",

journal = "Schizophrenia Bulletin",

issn = "0586-7614",

publisher = "Oxford University Press",

number = "4",

}

McGrath, JJ, Saha, S, Al-Hamzawi, AO, Alonso, J, Andrade, L, Borges, G, Bromet, EJ, Browne, MO, Bruffaerts, R, Caldas de Almeida, JM, Fayyad, J, Florescu, S, de Girolamo, G, Gureje, O, Hu, C, de Jonge, P, Kovess-Masfety, V, Lepine, JP, Lim, CCW, Navarro-Mateu, F, Piazza, M, Sampson, N, Posada-Villa, J, Kendler, KS & Kessler, RC 2016, 'Age of Onset and Lifetime Projected Risk of Psychotic Experiences: Cross-National Data From the World Mental Health Survey', Schizophrenia Bulletin, vol. 42, no. 4, pp. 933-941. https://doi.org/10.1093/schbul/sbw011

TY - JOUR

T1 - Age of Onset and Lifetime Projected Risk of Psychotic Experiences

T2 - Cross-National Data From the World Mental Health Survey

AU - McGrath, John J.

AU - Saha, Sukanta

AU - Al-Hamzawi, Ali O.

AU - Alonso, Jordi

AU - Andrade, Laura

AU - Borges, Guilherme

AU - Bromet, Evelyn J.

AU - Browne, Mark Oakley

AU - Bruffaerts, Ronny

AU - Caldas de Almeida, Jose M.

AU - Fayyad, John

AU - Florescu, Silvia

AU - de Girolamo, Giovanni

AU - Gureje, Oye

AU - Hu, Chiyi

AU - de Jonge, Peter

AU - Kovess-Masfety, Viviane

AU - Lepine, Jean Pierre

AU - Lim, Carmen C. W.

AU - Navarro-Mateu, Fernando

AU - Piazza, Maria

AU - Sampson, Nancy

AU - Posada-Villa, Jose

AU - Kendler, Kenneth S.

AU - Kessler, Ronald C.

PY - 2016/7

Y1 - 2016/7

N2 - Background: Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features. Methods: Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime prevalence of PE. Projected lifetime risk (at age 75 years) was estimated using a 2-part actuarial method. AOO distributions were described for the observed and projected estimates. We examined associations of AOO with PE type metric and annualized PE frequency. Results: Projected lifetime risk for PEs was 7.8% (SE = 0.3), slightly higher than lifetime prevalence (5.8%, SE = 0.2). The median (interquartile range; IQR) AOO based on projected lifetime estimates was 26 (17-41) years, indicating that PEs commence across a wide age range. The AOO distributions for PEs did not differ by sex. Early AOO was positively associated with number of PE types (F = 14.1, P

AB - Background: Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features. Methods: Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime prevalence of PE. Projected lifetime risk (at age 75 years) was estimated using a 2-part actuarial method. AOO distributions were described for the observed and projected estimates. We examined associations of AOO with PE type metric and annualized PE frequency. Results: Projected lifetime risk for PEs was 7.8% (SE = 0.3), slightly higher than lifetime prevalence (5.8%, SE = 0.2). The median (interquartile range; IQR) AOO based on projected lifetime estimates was 26 (17-41) years, indicating that PEs commence across a wide age range. The AOO distributions for PEs did not differ by sex. Early AOO was positively associated with number of PE types (F = 14.1, P

KW - epidemiology

KW - psychotic experiences

KW - age of onset

KW - lifetime prevalence

KW - World Mental Health Survey

KW - DELUSIONAL-LIKE EXPERIENCES

KW - POPULATION-BASED SURVEY

KW - GENERAL-POPULATION

KW - DISORDERS

KW - SYMPTOMS

KW - SCHIZOPHRENIA

KW - ASSOCIATION

KW - ADULTS

U2 - 10.1093/schbul/sbw011

DO - 10.1093/schbul/sbw011

M3 - Article

C2 - 27038468

VL - 42

SP - 933

EP - 941

JO - Schizophrenia Bulletin

JF - Schizophrenia Bulletin

SN - 0586-7614

IS - 4

ER -