Age of Onset and Lifetime Projected Risk of Psychotic Experiences: Cross-National Data From the World Mental Health Survey

John J. McGrath*, Sukanta Saha, Ali O. Al-Hamzawi, Jordi Alonso, Laura Andrade, Guilherme Borges, Evelyn J. Bromet, Mark Oakley Browne, Ronny Bruffaerts, Jose M. Caldas de Almeida, John Fayyad, Silvia Florescu, Giovanni de Girolamo, Oye Gureje, Chiyi Hu, Peter de Jonge, Viviane Kovess-Masfety, Jean Pierre Lepine, Carmen C. W. Lim, Fernando Navarro-MateuMaria Piazza, Nancy Sampson, Jose Posada-Villa, Kenneth S. Kendler, Ronald C. Kessler

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

51 Citations (Scopus)

Abstract

Background: Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features. Methods: Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime prevalence of PE. Projected lifetime risk (at age 75 years) was estimated using a 2-part actuarial method. AOO distributions were described for the observed and projected estimates. We examined associations of AOO with PE type metric and annualized PE frequency. Results: Projected lifetime risk for PEs was 7.8% (SE = 0.3), slightly higher than lifetime prevalence (5.8%, SE = 0.2). The median (interquartile range; IQR) AOO based on projected lifetime estimates was 26 (17-41) years, indicating that PEs commence across a wide age range. The AOO distributions for PEs did not differ by sex. Early AOO was positively associated with number of PE types (F = 14.1, P

Original languageEnglish
Pages (from-to)933-941
Number of pages9
JournalSchizophrenia Bulletin
Volume42
Issue number4
DOIs
Publication statusPublished - Jul-2016

Keywords

  • epidemiology
  • psychotic experiences
  • age of onset
  • lifetime prevalence
  • World Mental Health Survey
  • DELUSIONAL-LIKE EXPERIENCES
  • POPULATION-BASED SURVEY
  • GENERAL-POPULATION
  • DISORDERS
  • SYMPTOMS
  • SCHIZOPHRENIA
  • ASSOCIATION
  • ADULTS

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