Age-specific incidence and treatment patterns of head and neck cancer in the Netherlands-A cohort study

G. B. Halmos; L. Bras; S. Siesling; B. F. A. M. van der Laan; J. A. Langendijk; B. A. C. van Dijk

doi:10.1111/coa.12991

Age-specific incidence and treatment patterns of head and neck cancer in the Netherlands-A cohort study

G. B. Halmos^*
, L. Bras
, S. Siesling
, B. F. A. M. van der Laan
, J. A. Langendijk
, B. A. C. van Dijk

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

OBJECTIVES: To explore the incidence and treatment pattern of head and neck cancer in different age groups.

DESIGN: cohort study.

SETTING: Netherlands Cancer Registry.

PARTICIPANTS: All new primary head and neck cancer cases diagnosed between 2010 and 2014 were included and categorized in different age groups.

MAIN OUTCOME MEASURES: Tumour site, stage, treatment modality, location of diagnosis and treatment.

RESULTS: The study population was composed of 11,558 tumours. Oral cancer was the most common primary site (31%), followed by laryngeal (25%) and oropharyngeal cancer (22%). Ninety-six percent of the entire study population was diagnosed and/or treated in a certified head and neck oncology centre which was lower in the 80+ population (92%). Multimodality treatment was less frequently applied with increasing age (e.g. oral cavity: 17% in 80+ vs. 34% in 60-; p<0.001). The percentage of patients not receiving tumour directed treatment increased with age (e.g. oropharyngeal cancer: 25% in 80+ vs. 6% in 80-; p<0.001).

CONCLUSIONS: This study confirms that less multimodal and tumour directed treatment is applied with the increasing age of head and neck cancer patients. This article is protected by copyright. All rights reserved.

Original language	English
Pages (from-to)	317-324
Number of pages	8
Journal	Clinical Otolaryngology
Volume	43
Issue number	1
Early online date	26-Sept-2017
DOIs	https://doi.org/10.1111/coa.12991
Publication status	Published - Feb-2018

Keywords

GASTROESOPHAGEAL-REFLUX DISEASE
ESOPHAGEAL BOLUS TRANSIT
SECONDARY PERISTALSIS
GLOBUS SENSATION
CLEARANCE
STIMULATION
PHARYNGEUS
SYMPTOMS
MOTILITY

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Age-specific incidence and treatment patterns of head andneck cancer in the Netherlands—A cohort studyFinal publisher's version, 332 KBLicence: Taverne

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Additional file 2 of A two-stage genome-wide association study of radiation-induced acute toxicity in head and neck cancer
Naderi, E. (Creator), Crijns, A. P. G. (Creator), Steenbakkers, R. (Contributor), van den Hoek, A. (Contributor), Boezen, H. M. (Creator), Alizadeh, B. Z. (Creator) & Langendijk, J. A. (Creator), figshare, 27-Nov-2021
DOI: 10.6084/m9.figshare.17087902, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_A_two-stage_genome-wide_association_study_of_radiation-induced_acute_toxicity_in_head_and_neck_cancer/17087902
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Cite this

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title = "Age-specific incidence and treatment patterns of head and neck cancer in the Netherlands-A cohort study",

abstract = "OBJECTIVES: To explore the incidence and treatment pattern of head and neck cancer in different age groups.DESIGN: cohort study.SETTING: Netherlands Cancer Registry.PARTICIPANTS: All new primary head and neck cancer cases diagnosed between 2010 and 2014 were included and categorized in different age groups.MAIN OUTCOME MEASURES: Tumour site, stage, treatment modality, location of diagnosis and treatment.RESULTS: The study population was composed of 11,558 tumours. Oral cancer was the most common primary site (31\%), followed by laryngeal (25\%) and oropharyngeal cancer (22\%). Ninety-six percent of the entire study population was diagnosed and/or treated in a certified head and neck oncology centre which was lower in the 80+ population (92\%). Multimodality treatment was less frequently applied with increasing age (e.g. oral cavity: 17\% in 80+ vs. 34\% in 60-; p<0.001). The percentage of patients not receiving tumour directed treatment increased with age (e.g. oropharyngeal cancer: 25\% in 80+ vs. 6\% in 80-; p<0.001).CONCLUSIONS: This study confirms that less multimodal and tumour directed treatment is applied with the increasing age of head and neck cancer patients. This article is protected by copyright. All rights reserved.",

keywords = "GASTROESOPHAGEAL-REFLUX DISEASE, ESOPHAGEAL BOLUS TRANSIT, SECONDARY PERISTALSIS, GLOBUS SENSATION, CLEARANCE, STIMULATION, PHARYNGEUS, SYMPTOMS, MOTILITY",

author = "Halmos, \{G. B.\} and L. Bras and S. Siesling and \{van der Laan\}, \{B. F. A. M.\} and Langendijk, \{J. A.\} and \{van Dijk\}, \{B. A. C.\}",

year = "2018",

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doi = "10.1111/coa.12991",

language = "English",

volume = "43",

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AU - Halmos, G. B.

AU - Bras, L.

AU - Siesling, S.

AU - van der Laan, B. F. A. M.

AU - Langendijk, J. A.

AU - van Dijk, B. A. C.

PY - 2018/2

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N2 - OBJECTIVES: To explore the incidence and treatment pattern of head and neck cancer in different age groups.DESIGN: cohort study.SETTING: Netherlands Cancer Registry.PARTICIPANTS: All new primary head and neck cancer cases diagnosed between 2010 and 2014 were included and categorized in different age groups.MAIN OUTCOME MEASURES: Tumour site, stage, treatment modality, location of diagnosis and treatment.RESULTS: The study population was composed of 11,558 tumours. Oral cancer was the most common primary site (31%), followed by laryngeal (25%) and oropharyngeal cancer (22%). Ninety-six percent of the entire study population was diagnosed and/or treated in a certified head and neck oncology centre which was lower in the 80+ population (92%). Multimodality treatment was less frequently applied with increasing age (e.g. oral cavity: 17% in 80+ vs. 34% in 60-; p<0.001). The percentage of patients not receiving tumour directed treatment increased with age (e.g. oropharyngeal cancer: 25% in 80+ vs. 6% in 80-; p<0.001).CONCLUSIONS: This study confirms that less multimodal and tumour directed treatment is applied with the increasing age of head and neck cancer patients. This article is protected by copyright. All rights reserved.

AB - OBJECTIVES: To explore the incidence and treatment pattern of head and neck cancer in different age groups.DESIGN: cohort study.SETTING: Netherlands Cancer Registry.PARTICIPANTS: All new primary head and neck cancer cases diagnosed between 2010 and 2014 were included and categorized in different age groups.MAIN OUTCOME MEASURES: Tumour site, stage, treatment modality, location of diagnosis and treatment.RESULTS: The study population was composed of 11,558 tumours. Oral cancer was the most common primary site (31%), followed by laryngeal (25%) and oropharyngeal cancer (22%). Ninety-six percent of the entire study population was diagnosed and/or treated in a certified head and neck oncology centre which was lower in the 80+ population (92%). Multimodality treatment was less frequently applied with increasing age (e.g. oral cavity: 17% in 80+ vs. 34% in 60-; p<0.001). The percentage of patients not receiving tumour directed treatment increased with age (e.g. oropharyngeal cancer: 25% in 80+ vs. 6% in 80-; p<0.001).CONCLUSIONS: This study confirms that less multimodal and tumour directed treatment is applied with the increasing age of head and neck cancer patients. This article is protected by copyright. All rights reserved.

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KW - ESOPHAGEAL BOLUS TRANSIT

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KW - GLOBUS SENSATION

KW - CLEARANCE

KW - STIMULATION

KW - PHARYNGEUS

KW - SYMPTOMS

KW - MOTILITY

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EP - 324

JO - Clinical Otolaryngology

JF - Clinical Otolaryngology

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Age-specific incidence and treatment patterns of head and neck cancer in the Netherlands-A cohort study

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Additional file 2 of A two-stage genome-wide association study of radiation-induced acute toxicity in head and neck cancer

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