Allergen immunotherapy for allergic rhinoconjunctivitis: protocol for a systematic review

Sangeeta Dhami*, Ulugbek Nurmatov, Graham Roberts, Oliver Pfaar, Antonella Muraro, Ignacio J. Ansotegui, Moises Calderon, Cemal Cingi, Pascal Demoly, Stephen Durham, Ronald Gerth van Wijk, Susanne Halken, Eckard Hamelmann, Peter Hellings, Lars Jacobsen, Edward Knol, Desiree Larenas Linnemann, Sandra Lin, Vivian Maggina, H. N. G. Oude ElberinkGiovanni Pajno, Ruby Panwankar, Elideanna Pastorello, Constantinos Pitsios, Giuseppina Rotiroti, Frans Timmermans, Olympia Tsilochristou, Eva-Maria Varga, Jamie Wilkinson, Andrew Williams, Margitta Worm, Luo Zhang, Aziz Sheikh

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Allergic Rhinoconjunctivitis. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of allergic rhinoconjunctivitis.

Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre- defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised.

Conclusion: The findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.

Original languageEnglish
Article number12
Number of pages6
JournalClinical and translational allergy
Volume6
DOIs
Publication statusPublished - 22-Mar-2016

Keywords

  • Allergy
  • Allergic rhinoconjunctivitis
  • Allergen immunotherapy
  • Rhinitis
  • RHINITIS
  • ASTHMA
  • IMPACT
  • BIAS

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