Allergic contact dermatitis caused by canvas sneakers: The search for the allergen

J.M. Meijer, M.L.A. Schuttelaar

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Thiurams, dithiocarbamates and mercaptobenzothiazoles are the main groups of allergenic rubber accelerators that can cause allergic contact dermatitis to shoes. In this case report, pruritis, erythema and erythematous papules developed on the dorsal side of the feet after wearing canvas sneakers. After patch testing including a rubber additives series a contact allergy to a thiuram compound was suspected. Eventually after patch testing with extracts from shoe materials and further chemical analysis with thin-layer chromatography and gas chromatography- mass spectrometry the culprit allergen was identified as a newly formed compound dimethylthiocarbamylbenzothiazol sulfide (DMTBS). DMTBS is formed during the vulcanization process of the rubber materials of the canvas sneakers.
Translated title of the contributionAllergic contact dermatitis caused by canvas sneakers: The search for the allergen
Original languageDutch
Pages (from-to)264-267
Number of pages4
JournalNederlands Tijdschrift voor Dermatologie en Venereologie
Volume27
Issue number6
Publication statusPublished - 8-Mar-2017

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