Allergy-specific immunotherapy compositions for use in the treatment of house-dust mite allergy

Gerrit Jan Willem Euverink (Inventor), Laura Hesse (Inventor), Martijn Christiaan Nawijn (Inventor), Adrianus Cornelis van der Graaf (Inventor)

Research output: Patent

Abstract

The present invention relates to a composition comprising purified natural Der p1 and purified natural Der p2 allergens for use in the treatment of house-dust mite allergy in mammals, like humans. The invention further pertains pharmaceutical compositions for allergy-specific immune therapy. Specifically, the invention discloses reduced responsiveness to subsequent house dust mite allergen exposure after treatment with a pharmaceutical composition comprising purified natural Der p1 and purified natural Der p2 characterized by reduction in Th2 cell activity and reduction in CCL20 release.
Original languageEnglish
Patent numberWO2016193126
Priority date29/05/2015
Publication statusPublished - 8-Dec-2016

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