Allergy to mites: relation to lung function and airway hyperresponsiveness

S van der Heide*, AEJ Dubois, HF Kauffman, JGR de Monchy

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Abstract

Exposure to house-dust-mite allergens is an important cause of allergic reactions in sensitized patients. In community-based studies, sensitization to house-duct mites, as ascertained by a positive skin test or by an increased allergen-specific IgE level in serum, is associated with both diminished lung function and enhanced airway hyperresponsiveness. Sensitization to house-dust mites is an independent risk factor for the development of asthma, especially in areas which favor the growth of house-dust mites. In studies with asthmatic patients, however, the relationship between sensitization to mites and lung function or airway hyperresponsiveness is less clear. The selection of asthmatic individuals (with sensitization to other inhalant allergens) and the use of medication such as inhaled steroids may interfere with the demonstration of a possible association between mite allergy and lung function or airway hyperresponsiveness in asthmatic patients.

Original languageEnglish
Pages (from-to)104-107
Number of pages4
JournalAllergy
Volume53
Publication statusPublished - 1998
EventInternational Scientific Workshop on the House-Dust Mite - Its Biology and Role in Allergy - , Norway
Duration: 4-Sep-19977-Sep-1997

Keywords

  • airway hyperresponsiveness
  • allergy
  • asthma
  • house-dust mites
  • lung function
  • SKIN-TEST REACTIVITY
  • HOUSE-DUST MITES
  • BRONCHIAL RESPONSIVENESS
  • RESPIRATORY SYMPTOMS
  • PULMONARY-FUNCTION
  • CHILDREN
  • ASTHMA
  • EXPOSURE
  • SENSITIZATION
  • POPULATION

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