AMINO-ACIDS FOR THE MEASUREMENT OF PROTEIN-SYNTHESIS INVIVO BY PET

W VAALBURG, HH COENEN, C CROUZEL, PH ELSINGA, B LANGSTROM, C LEMAIRE, GJ MEYER

Research output: Contribution to journalArticleAcademicpeer-review

94 Citations (Scopus)

Abstract

Aspects of the suitability of various labelled amino acids for measuring their local incorporation into proteins by positron emission tomography, especially radiochemical aspects including choice of radionuclide, position of label and ease of preparation, are discussed.

Original languageEnglish
Pages (from-to)227-237
Number of pages11
JournalNuclear Medicine and Biology
Volume19
Issue number2
Publication statusPublished - Feb-1992

Keywords

  • POSITRON EMISSION TOMOGRAPHY
  • BLOOD-BRAIN-BARRIER
  • SYNTHESIS RATES
  • ELECTROPHILIC RADIOFLUORINATION
  • PHENYLALANINE TRANSPORT
  • 7-DAY-OLD RATS
  • TYROSINE
  • METABOLISM
  • L-<METHYL-C-11>METHIONINE
  • RADIOPHARMACEUTICALS

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