An unexpected role for bile acid synthesis in adaptation to low temperature

Folkert Kuipers; Albert K. Groen

doi:10.1038/nm.4365

An unexpected role for bile acid synthesis in adaptation to low temperature

Folkert Kuipers^*, Albert K. Groen

^*Corresponding author for this work

Research output: Contribution to journal › Editorial › Academic › peer-review

2 Citations (Scopus)

Abstract

Enhanced conversion of dietary cholesterol to bile acids through the alternative pathway leads to cold-associated, metabolically beneficial changes in the intestinal microbiome and to elevated bile acid levels that contribute to adaptive thermogenesis.

Original language	English
Pages (from-to)	800-802
Number of pages	3
Journal	Nature Medicine
Volume	23
Issue number	7
DOIs	https://doi.org/10.1038/nm.4365
Publication status	Published - Jul-2017

Keywords

ENERGY-EXPENDITURE
METABOLISM
ACTIVATION

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An unexpected role for bile acid synthesis in adaptation to low temperature
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title = "An unexpected role for bile acid synthesis in adaptation to low temperature",

abstract = "Enhanced conversion of dietary cholesterol to bile acids through the alternative pathway leads to cold-associated, metabolically beneficial changes in the intestinal microbiome and to elevated bile acid levels that contribute to adaptive thermogenesis.",

keywords = "ENERGY-EXPENDITURE, METABOLISM, ACTIVATION",

author = "Folkert Kuipers and Groen, {Albert K.}",

year = "2017",

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AU - Groen, Albert K.

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AB - Enhanced conversion of dietary cholesterol to bile acids through the alternative pathway leads to cold-associated, metabolically beneficial changes in the intestinal microbiome and to elevated bile acid levels that contribute to adaptive thermogenesis.

KW - ENERGY-EXPENDITURE

KW - METABOLISM

KW - ACTIVATION

U2 - 10.1038/nm.4365

DO - 10.1038/nm.4365

M3 - Editorial

C2 - 28697185

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VL - 23

SP - 800

EP - 802

JO - Nature Medicine

JF - Nature Medicine

IS - 7

ER -

An unexpected role for bile acid synthesis in adaptation to low temperature

Abstract

Keywords

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