Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction Rationale and Design of the PARAGON-HF Trial

Scott D. Solomon; Adel R. Rizkala; Jianjian Gong; Wenyan Wang; Inder S. Anand; Junbo Ge; Carolyn S. P. Lam; Aldo P. Maggioni; Felipe Martinez; Milton Packer; Marc A. Pfeffer; Burkert Pieske; Margaret M. Redfield; Jean L. Rouleau; Dirk J. Van Veldhuisen; Faiez Zannad; Michael R. Zile; Akshay S. Desai; Victor C. Shi; Martin P. Lefkowitz; John. J. V. McMurray

doi:10.1016/j.jchf.2017.04.013

Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction Rationale and Design of the PARAGON-HF Trial

Scott D. Solomon^*, Adel R. Rizkala, Jianjian Gong, Wenyan Wang, Inder S. Anand, Junbo Ge, Carolyn S. P. Lam, Aldo P. Maggioni, Felipe Martinez, Milton Packer, Marc A. Pfeffer, Burkert Pieske, Margaret M. Redfield, Jean L. Rouleau, Dirk J. Van Veldhuisen, Faiez Zannad, Michael R. Zile, Akshay S. Desai, Victor C. Shi, Martin P. LefkowitzJohn. J. V. McMurray

^*Corresponding author for this work

Cardiovascular Centre (CVC)

Research output: Contribution to journal › Review article › Academic › peer-review

202 Citations (Scopus)

Original language	English
Pages (from-to)	471-482
Number of pages	12
Journal	JACC. Heart failure
Volume	5
Issue number	7
DOIs	https://doi.org/10.1016/j.jchf.2017.04.013
Publication status	Published - Jul-2017

Keywords

IMPAIRED SYSTOLIC FUNCTION
DIASTOLIC DYSFUNCTION
CARDIAC STRUCTURE
SPIRONOLACTONE
OUTCOMES
DISEASE
EVENTS
LCZ696

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10.1016/j.jchf.2017.04.013

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Angiotensin Receptor Neprilysin
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Solomon, S. D., Rizkala, A. R., Gong, J., Wang, W., Anand, I. S., Ge, J., Lam, C. S. P., Maggioni, A. P., Martinez, F., Packer, M., Pfeffer, M. A., Pieske, B., Redfield, M. M., Rouleau, J. L., Van Veldhuisen, D. J., Zannad, F., Zile, M. R., Desai, A. S., Shi, V. C., ... McMurray, J. J. V. (2017). Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction Rationale and Design of the PARAGON-HF Trial. JACC. Heart failure, 5(7), 471-482. https://doi.org/10.1016/j.jchf.2017.04.013

Solomon, Scott D. ; Rizkala, Adel R. ; Gong, Jianjian ; Wang, Wenyan ; Anand, Inder S. ; Ge, Junbo ; Lam, Carolyn S. P. ; Maggioni, Aldo P. ; Martinez, Felipe ; Packer, Milton ; Pfeffer, Marc A. ; Pieske, Burkert ; Redfield, Margaret M. ; Rouleau, Jean L. ; Van Veldhuisen, Dirk J. ; Zannad, Faiez ; Zile, Michael R. ; Desai, Akshay S. ; Shi, Victor C. ; Lefkowitz, Martin P. ; McMurray, John. J. V. / Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction Rationale and Design of the PARAGON-HF Trial. In: JACC. Heart failure. 2017 ; Vol. 5, No. 7. pp. 471-482.

@article{fe311b5138db41129ae0c200aad3fe7c,

title = "Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction Rationale and Design of the PARAGON-HF Trial",

keywords = "IMPAIRED SYSTOLIC FUNCTION, DIASTOLIC DYSFUNCTION, CARDIAC STRUCTURE, SPIRONOLACTONE, OUTCOMES, DISEASE, EVENTS, LCZ696",

author = "Solomon, {Scott D.} and Rizkala, {Adel R.} and Jianjian Gong and Wenyan Wang and Anand, {Inder S.} and Junbo Ge and Lam, {Carolyn S. P.} and Maggioni, {Aldo P.} and Felipe Martinez and Milton Packer and Pfeffer, {Marc A.} and Burkert Pieske and Redfield, {Margaret M.} and Rouleau, {Jean L.} and {Van Veldhuisen}, {Dirk J.} and Faiez Zannad and Zile, {Michael R.} and Desai, {Akshay S.} and Shi, {Victor C.} and Lefkowitz, {Martin P.} and McMurray, {John. J. V.}",

year = "2017",

month = jul,

doi = "10.1016/j.jchf.2017.04.013",

language = "English",

volume = "5",

pages = "471--482",

journal = "JACC. Heart failure",

issn = "2213-1779",

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Solomon, SD, Rizkala, AR, Gong, J, Wang, W, Anand, IS, Ge, J, Lam, CSP, Maggioni, AP, Martinez, F, Packer, M, Pfeffer, MA, Pieske, B, Redfield, MM, Rouleau, JL, Van Veldhuisen, DJ, Zannad, F, Zile, MR, Desai, AS, Shi, VC, Lefkowitz, MP & McMurray, JJV 2017, 'Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction Rationale and Design of the PARAGON-HF Trial', JACC. Heart failure, vol. 5, no. 7, pp. 471-482. https://doi.org/10.1016/j.jchf.2017.04.013

Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction Rationale and Design of the PARAGON-HF Trial. / Solomon, Scott D.; Rizkala, Adel R.; Gong, Jianjian; Wang, Wenyan; Anand, Inder S.; Ge, Junbo; Lam, Carolyn S. P.; Maggioni, Aldo P.; Martinez, Felipe; Packer, Milton; Pfeffer, Marc A.; Pieske, Burkert; Redfield, Margaret M.; Rouleau, Jean L.; Van Veldhuisen, Dirk J.; Zannad, Faiez; Zile, Michael R.; Desai, Akshay S.; Shi, Victor C.; Lefkowitz, Martin P.; McMurray, John. J. V.

In: JACC. Heart failure, Vol. 5, No. 7, 07.2017, p. 471-482.

Research output: Contribution to journal › Review article › Academic › peer-review

TY - JOUR

T1 - Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction Rationale and Design of the PARAGON-HF Trial

AU - Solomon, Scott D.

AU - Rizkala, Adel R.

AU - Gong, Jianjian

AU - Wang, Wenyan

AU - Anand, Inder S.

AU - Ge, Junbo

AU - Lam, Carolyn S. P.

AU - Maggioni, Aldo P.

AU - Martinez, Felipe

AU - Packer, Milton

AU - Pfeffer, Marc A.

AU - Pieske, Burkert

AU - Redfield, Margaret M.

AU - Rouleau, Jean L.

AU - Van Veldhuisen, Dirk J.

AU - Zannad, Faiez

AU - Zile, Michael R.

AU - Desai, Akshay S.

AU - Shi, Victor C.

AU - Lefkowitz, Martin P.

AU - McMurray, John. J. V.

PY - 2017/7

Y1 - 2017/7

KW - IMPAIRED SYSTOLIC FUNCTION

KW - DIASTOLIC DYSFUNCTION

KW - CARDIAC STRUCTURE

KW - SPIRONOLACTONE

KW - OUTCOMES

KW - DISEASE

KW - EVENTS

KW - LCZ696

U2 - 10.1016/j.jchf.2017.04.013

DO - 10.1016/j.jchf.2017.04.013

M3 - Review article

VL - 5

SP - 471

EP - 482

JO - JACC. Heart failure

JF - JACC. Heart failure

SN - 2213-1779

IS - 7

ER -