Anorexia and Bulimia Nervosa in Same-Sex and Opposite-Sex Twins: Lack of Association With Twin Type in a Nationwide Study of Finnish Twins

Anu Raevuori*, Jaakko Kaprio, Hans W. Hoek, Elina Sihvola, Aila Rissanen, Anna Keski-Rahkonen

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    34 Citations (Scopus)

    Abstract

    Objective: The authors tested the hypothesis that either prenatal feminization or masculinization hormone influences in utero or later socialization affects the risk for anorexia and bulimia nervosa and disordered eating in members of opposite-sex twin pairs.

    Method: Finnish twins (N=2,426 women, N=1,962 men with known zygosity) from birth cohorts born 1974-1979 were assessed at age 22 to 28 years with a questionnaire for eating disorder symptoms. Based on the questionnaire screen, women (N=292), men (N=53), and their cotwins were interviewed to assess diagnoses of anorexia nervosa and bulimia nervosa (per DSM-IV and broad criteria).

    Results: In women from opposite-sex twin pairs, the prevalence of DSM-IV or broad anorexia nervosa was not significantly different than that of women from monozygotic pairs or same-sex dizygotic pairs. Of the five male anorexia nervosa probands, only one was from an opposite-sex twin pair. Bulimia nervosa in men was too rare to be assessed by zygosity; the prevalence of DSM-IV or broad bulimia nervosa did not differ in women from opposite-versus same-sex twin pairs. In both sexes, the overall profile of indicators on eating disorders was rather similar between individuals from opposite- and same-sex pairs.

    Conclusions: The authors found little evidence that the risk for anorexia nervosa, bulimia nervosa, or disordered eating was associated with zygosity or sex composition of twin pairs, thus making it unlikely that in utero femininization or masculinization or socialization effects of growing up with an opposite-sex twin have a major influence on the later development of eating disorders.

    Original languageEnglish
    Pages (from-to)1604-1610
    Number of pages7
    JournalAmerican Journal of Psychiatry
    Volume165
    Issue number12
    Publication statusPublished - Dec-2008

    Keywords

    • PROSPECTIVE RISK-FACTORS
    • EATING-DISORDERS
    • PHYSICAL-ACTIVITY
    • COMMUNITY
    • HERITABILITY
    • POPULATION
    • PREVALENCE
    • BEHAVIORS
    • HORMONES
    • WOMEN

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