Aromatic peptide amphiphiles: significance of the Fmoc moiety

Scott Fleming; Sisir Debnath; Pim W. J. M. Frederix; Tell Tuttle; Rein V. Ulijn

doi:10.1039/c3cc45822a

Aromatic peptide amphiphiles: significance of the Fmoc moiety

Scott Fleming^*, Sisir Debnath, Pim W. J. M. Frederix, Tell Tuttle, Rein V. Ulijn

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

118 Citations (Scopus)

Abstract

Aromatic peptide amphiphile hydrogelators commonly utilise the fluorenyl-9-methoxycarbonyl moiety as an N-terminal capping group. Material properties and spectroscopic techniques show the influence of alternative linkers between the fluorenyl moiety and the peptide. This study establishes whether methoxycarbonyl is an optimal or mainly convenient linker, for this class of self-assembling systems.

Original language	English
Pages (from-to)	10587-10589
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	90
DOIs	https://doi.org/10.1039/c3cc45822a
Publication status	Published - 2013
Externally published	Yes

Keywords

SUPRAMOLECULAR HYDROGELS
RESTRICTED ROTATION
BETA-SHEETS
SELF
NAPHTHALENE
ARCHITECTURE
NANOFIBERS
DIPEPTIDES
RESONANCE
AMIDES

Access to Document

10.1039/c3cc45822a

Handle.net

Persistent link

Cite this

@article{98e21e8ab62f4fbfadc266501f03abd6,

title = "Aromatic peptide amphiphiles: significance of the Fmoc moiety",

abstract = "Aromatic peptide amphiphile hydrogelators commonly utilise the fluorenyl-9-methoxycarbonyl moiety as an N-terminal capping group. Material properties and spectroscopic techniques show the influence of alternative linkers between the fluorenyl moiety and the peptide. This study establishes whether methoxycarbonyl is an optimal or mainly convenient linker, for this class of self-assembling systems.",

keywords = "SUPRAMOLECULAR HYDROGELS, RESTRICTED ROTATION, BETA-SHEETS, SELF, NAPHTHALENE, ARCHITECTURE, NANOFIBERS, DIPEPTIDES, RESONANCE, AMIDES",

author = "Scott Fleming and Sisir Debnath and Frederix, {Pim W. J. M.} and Tell Tuttle and Ulijn, {Rein V.}",

year = "2013",

doi = "10.1039/c3cc45822a",

language = "English",

volume = "49",

pages = "10587--10589",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "ROYAL SOC CHEMISTRY",

number = "90",

}

TY - JOUR

T1 - Aromatic peptide amphiphiles

T2 - significance of the Fmoc moiety

AU - Fleming, Scott

AU - Debnath, Sisir

AU - Frederix, Pim W. J. M.

AU - Tuttle, Tell

AU - Ulijn, Rein V.

PY - 2013

Y1 - 2013

N2 - Aromatic peptide amphiphile hydrogelators commonly utilise the fluorenyl-9-methoxycarbonyl moiety as an N-terminal capping group. Material properties and spectroscopic techniques show the influence of alternative linkers between the fluorenyl moiety and the peptide. This study establishes whether methoxycarbonyl is an optimal or mainly convenient linker, for this class of self-assembling systems.

AB - Aromatic peptide amphiphile hydrogelators commonly utilise the fluorenyl-9-methoxycarbonyl moiety as an N-terminal capping group. Material properties and spectroscopic techniques show the influence of alternative linkers between the fluorenyl moiety and the peptide. This study establishes whether methoxycarbonyl is an optimal or mainly convenient linker, for this class of self-assembling systems.

KW - SUPRAMOLECULAR HYDROGELS

KW - RESTRICTED ROTATION

KW - BETA-SHEETS

KW - SELF

KW - NAPHTHALENE

KW - ARCHITECTURE

KW - NANOFIBERS

KW - DIPEPTIDES

KW - RESONANCE

KW - AMIDES

U2 - 10.1039/c3cc45822a

DO - 10.1039/c3cc45822a

M3 - Article

SN - 1359-7345

VL - 49

SP - 10587

EP - 10589

JO - Chemical Communications

JF - Chemical Communications

IS - 90

ER -

Aromatic peptide amphiphiles: significance of the Fmoc moiety

Abstract

Keywords

Access to Document

Handle.net

Fingerprint

Cite this