Artificial molecular motors

Salma Kassem, Thomas van Leeuwen, Anouk S. Lubbe, Miriam R. Wilson, Ben L. Feringa*, David A. Leigh*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

705 Citations (Scopus)
912 Downloads (Pure)

Abstract

Motor proteins are nature's solution for directing movement at the molecular level. The field of artificial molecular motors takes inspiration from these tiny but powerful machines. Although directional motion on the nanoscale performed by synthetic molecular machines is a relatively new development, significant advances have been made. In this review an overview is given of the principal designs of artificial molecular motors and their modes of operation. Although synthetic molecular motors have also found widespread application as (multistate) switches, we focus on the control of directional movement, both at the molecular scale and at larger magnitudes. We identify some key challenges remaining in the field.

Original languageEnglish
Article numberC7CS00245A
Pages (from-to)2592-2621
Number of pages30
JournalChemical Society Reviews
Volume46
Issue number9
DOIs
Publication statusPublished - 7-May-2017

Keywords

  • UNIDIRECTIONAL ROTARY MOTION
  • SINGLE STEREOGENIC CENTER
  • SYNTHETIC SMALL-MOLECULE
  • BOND ROTATION
  • STRUCTURAL MODIFICATION
  • INFORMATION RATCHET
  • VISIBLE-LIGHT
  • DNA WALKER
  • OVERCROWDED ALKENES
  • DRIVEN

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