Artificial nanopores and uses and methods relating thereto

Giovanni Maglia (Inventor), Shengli Zhang (Inventor)

Research output: Patent

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Abstract

The invention relates to the field of nanopores and the use thereof in analyzing biopolymers, including polypeptides and polynucleotides. Provided is an artificial nanopore comprising a multimeric assembly of subunits, each subunit comprising (i) the transmembrane (TM) sequence of a β-barrel or α-helical pore forming protein fused to the amino acid sequence of (ii) a subunit of a ring-forming protein capable of controlling the transport of a polypeptide or polynucleotide across the TM region of the assembly.
Original languageEnglish
Patent numberWO2021101378
Priority date19/11/2019
Filing date19/11/2020
Publication statusPublished - 27-May-2021

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