ASD Symptom Severity in Adolescence of Individuals Diagnosed with PDD-NOS in Childhood: Stability and the Relation with Psychiatric Comorbidity and Societal Participation

A. Louwerse*, M. L. J. M. Eussen, J. Van der Ende, P. F. A. de Nijs, A. R. Van Gool, L. P. Dekker, C. Verheij, F. Verheij, F. C. Verhulst, K. Greaves-Lord

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

31 Citations (Scopus)
23 Downloads (Pure)

Abstract

The current 7-year follow-up study investigated: (1) the stability of ASD severity, and (2) associations of ASD severity in adolescence with (a) childhood and concurrent psychiatric comorbidity, and (b) concurrent societal functioning. The Autism Diagnostic Observation Schedule (ADOS) and the Diagnostic Interview Schedule for Children were administered in childhood (ages 6-12) and in adolescence (ages 12-20) to 72 individuals with a pervasive developmental disorder-not otherwise specified (PDD-NOS). ADOS calibrated severity scores showed a large stability (r = .51). Psychiatric comorbidity in childhood and adolescence were not associated with ASD severity in adolescence. Mental health care use (87 %) and special education needs were high (71 %). Reevaluation of ASD severity and psychiatric comorbidity later in life seem useful when PDD-NOS is diagnosed in childhood.

Original languageEnglish
Pages (from-to)3908-3918
Number of pages11
JournalJournal of Autism and Developmental Disorders
Volume45
Issue number12
DOIs
Publication statusPublished - Dec-2015
Externally publishedYes

Keywords

  • Autism spectrum disorders (ASD)
  • Pervasive developmental disorder-not otherwise specified (PDD-NOS)
  • Comorbid psychiatric disorders
  • Follow-up
  • Autism Diagnostic Observation Schedule (ADOS-2)
  • Symptom severity
  • Societal functioning
  • AUTISM SPECTRUM DISORDERS
  • OBSERVATION SCHEDULE
  • YOUNG-ADULTS
  • CHILDREN
  • POPULATION
  • AGE
  • ANXIETY
  • SCORES
  • COMMUNICATION
  • EPIDEMIOLOGY

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