Asymmetric Synthesis of β-Lactams via Amine Additions to 5(R)-Menthyloxy-2[5H]-Furanone.

Marcel Lubben, Bernard Feringa

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Abstract

The enantioselective synthesis of a N-benzyl substituted β-lactam, a precursor for carbapenem antibiotics, starting from the chiral synthon 5(R)-menthyloxy-2[5H]-furanone, is described.
Original languageEnglish
Number of pages4
JournalTetrahedron%3A Asymmetry
Volume2
Issue number8
DOIs
Publication statusPublished - 1991

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