CP violation in B-S(0) -(B) over bar (0)(S) oscillations is expected at the 10(-5) level in the Standard Model but could be enhanced by New Physics. Using B-S(0) -> D(S)(-)l(+)v(l) decays, LHCb has recently reported the new result (0.39 +/- 0.33) x 10(-2) of the corresponding observable a(Sl)(S). We point out that other current B decay data imply a(Sl)(S) = (0.004 0.075) x 10(-2). In view of this strong constraint, we propose to use B-S(0) -> D(S)(-)l(+)v(l) and similar flavor -specific decays as a new tool to determine both the production asymmetry between B-S(0) and (B) over bar (0)(S) mesons, and the CP asymmetry in the subsequent D-S(+/-) decays. The former serves as input for analyses of CP violation in B-S(0) channels, with significant room for improvement, while the latter offers an exciting laboratory for New Physics. (C) 2017 The Author(s). Published by Elsevier B.V.