Back cover: Multifunctional Biomimetic Nanovaccines Based on Photothermal and Weak-Immunostimulatory Nanoparticulate Cores for the Immunotherapy of Solid Tumors (Adv. Mater. 9/2022)

Jiachen Li, Di Huang, Ruoyu Cheng, Patrícia Figueiredo, Flavia Fontana, Alexandra Correia, Shiqi Wang, Zehua Liu, Marianna Kemell, Giulia Torrieri, Ermei M. Mäkilä, Jarno J. Salonen, Jouni Hirvonen, Yan Gao, Jialiang Li, Zhenyang Luo, Hélder A. Santos, Bing Xia

Research output: Non-textual formDigital or Visual ProductsAcademic

Abstract

Nanovaccines A cancer cell membrane@porous silicon nanoparticles@Au nanovaccine is developed by Zhenyang Luo, Hélder A. Santos, Bing Xia, and co-workers in article number 2108012, based on weak-immunostimulatory porous silicon@Au nanoparticulate cores and multi-antigenic cancer cell membranes. These exogenous nanovaccines boost antitumor immunity, preventing the occurrence of solid tumors, and significantly inhibiting the growth and metastasis of solid tumors after photothermal therapy combined with immune checkpoint inhibitors.
Original languageEnglish
DOIs
Publication statusPublished - 3-Mar-2022

Keywords

  • antitumor immune response
  • biomimetic nanovaccines
  • cancer cell membranes
  • photothermal synergized immunotherapy
  • porous silicon@Au nanocomposites

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