Bacterial interactions with nanostructured surfaces

Yafei Luan, Sidi Liu, Maria Pihl, Henny C. van der Mei, Jian Liu, Ferdi Hizal, Chang-Hwan Choi, Hong Chen, Yijin Ren, Henk J. Busscher

Research output: Contribution to journalReview articlepeer-review

34 Citations (Scopus)

Abstract

Nanostructured surfaces are called "promising" to control bacterial adhesion and biofilm formation. Initial adhesion is followed by emergence of surface-programmed bacterial properties and biofilm growth. A easy distinction between nanostructured surfaces can be made on basis of periodic-or random-occurrence of nanostructured features, although often nanostructured surfaces are microstructured due to merging of their nanofeatures. Characterization of nanostructured surfaces is not trivial due to the myriad of different nanoscaled morphologies. Both superhydrophobic and hydrophilic, nano structured surfaces generally yield low bacterial adhesion. On smooth surfaces, bacteria deform when adhering, causing membrane surface tension changes and accompanying responses yielding emergent properties. Adhesion to nano structured surfaces, causes multiple cell wall deformation sites when bacteria are adhering in valleys, while in case of hill-top adhesion, highly localized cell wall deformation occurs. Accordingly, bacterial adhesion to nanostructured surfaces yields emergent responses that range from pressure-induced EPS production to cell wall rupture and death, based upon which nanostructured surfaces are consistently called "promising" for bacterial adhesion and biofilm control. Other promising features of nanostructured surfaces are increased antibiotic housing, thermal effects and photo-induced ROS production, but the latter two promises are largely based on properties of suspended nanoparticles and may not hold when particles are comprised in nanostructured coatings or materials. Moreover, in order to bring nanostructured coatings and materials to application, experiments are needed that go beyond the current limit of the laboratory bench.

Original languageEnglish
Pages (from-to)170-189
Number of pages20
JournalCurrent opinion in colloid & interface science
Volume38
DOIs
Publication statusPublished - Nov-2018

Keywords

  • Bacteria
  • Nanopillared surfaces
  • Bacterial cell wall
  • EPS
  • Surface roughness
  • Wettability
  • GOLD NANOPARTICLE LAYERS
  • ATOMIC-FORCE MICROSCOPE
  • TITANIUM SURFACES
  • STAPHYLOCOCCUS-AUREUS
  • PHOTODYNAMIC THERAPY
  • NANOCOMPOSITE COATINGS
  • PHYSICO-CHEMISTRY
  • ESCHERICHIA-COLI
  • NANOWIRE ARRAYS
  • ADHESION FORCE

Cite this