Battle between plants as antioxidants with free radicals in human body

Fatemeh Jamshidi-Kia, Joko Priyanto Wibowo, Mostafa Elachouri, Rohollah Masumi, Alizamen Salehifard-Jouneghani, Zohreh Abolhassanzadeh*, Zahra Lorigooini*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

48 Citations (Scopus)
150 Downloads (Pure)


Free radicals are constructed by natural physiological activities in the human cells as well as in the environment. They may be produced as a result of diet, smoking, exercise, inflammation, exposure to sunlight, air pollutants, stress, alcohol and drugs. Imbalanced redox status may lead to cellular oxidative stress, which can damage the cells of the body, resulting in an incidence of various diseases. If the endogenous antioxidants do not stop the production of reactive metabolites, they will be needed to bring about a balance in redox status. Natural antioxidants, for example plants, play an important part in this context. This paper seeks to report the available evidence about oxidative stress and the application of plants as antioxidant agents to fight free radicals in the human body. For this purpose, to better understand oxidative stress, the principles of free radical production, the role of free radicals in diseases, antioxidant defense mechanisms, and the role of herbs and diet in oxidative stress are discussed.

Original languageEnglish
Pages (from-to)191-199
Number of pages9
JournalJournal of HerbMed Pharmacology
Issue number3
Publication statusPublished - 2020


  • Antioxidant
  • Free radicals
  • Human health
  • Oxidative stress
  • Plant

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