Bilateral one-stage single-port sympathicotomy in primary focal hyperhidrosis, a prospective cohort study: treat earlier?

Michiel Kuijpers*, Gwen Peeters, Petra W. Harms, Wobbe Bouma, Mike J. de Jongste, Massimo A. Mariani, Theo J. Klinkenberg

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
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BackgroundPrimary Focal Hyperhidrosis (PFH) has a detrimental effect on Quality of Life. Repetitive, non-curative symptomatic strategies dominate current treatment of PFH, in spite of the availability of an effective and permanent curative treatment like Endoscopic Thoracic Sympathectomy (ETS). Current surgical optimization may allow for a re-established position of sympathetic modulation in this treatment algorithm. We sought to evaluate the safety, effectiveness, and long-term results of a Bilateral One-stage Single-port Sympathicotomy (BOSS) procedure in PFH patients and to identify subgroups benefitting most.MethodsProspective analysis of 163 patients, 35 (21.5%) underwent Rib-3 (R3) BOSS for palmar PFH, 58 (35.6%) R3-R5 BOSS for axillary PFH and 70 (42.9%) R3-R5 BOSS for combined palmar/axillary PFH. Effectiveness was measured using Skindex-29 and the Hyperhidrosis Disease Severity Scale (HDSS).ResultsOverall Skindex-29-rating (46.514.8 preoperatively vs 20.1 +/- 20.6 postoperatively, p0.45 preoperatively vs 1.82 +/- 0.86 postoperatively, p

Original languageEnglish
Article number50
Number of pages7
JournalJournal of cardiothoracic surgery
Issue number1
Publication statusPublished - 25-Mar-2021


  • Palmar
  • Hyperhidrosis
  • Sweating
  • Sympathicotomy
  • Sympathectomy
  • VATS
  • Single-port

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