Bile Acid Look-Alike Controls Life Span in C. elegans

Albert K. Groen*, Folkert Kuipers

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademicpeer-review

6 Citations (Scopus)

Abstract

Extensive transcriptional networks maintain sterol homeostasis across species, underscoring the importance of sterol balance for healthy life. Magner et al. (2013) now show that, in C. elegans, the nuclear receptor NHR-8 is key in regulation of cholesterol balance and production of dafachronic acid, a bile acid-like steroid that controls longevity.

Original languageEnglish
Pages (from-to)151-152
Number of pages3
JournalCell metabolism
Volume18
Issue number2
DOIs
Publication statusPublished - 6-Aug-2013

Keywords

  • LONGEVITY

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