Biochemical Indicators of In-Hospital Complications Following Pancreatic Surgery

Biku J. John; Sanjay Wijeyekoon; Nienke Warnaar; Prasoona Shasi; Sakirullah H. Rahman; B. R. Davidson; C. Fusai

Biochemical Indicators of In-Hospital Complications Following Pancreatic Surgery

Biku J. John^*, Sanjay Wijeyekoon, Nienke Warnaar, Prasoona Shasi, Sakirullah H. Rahman, B. R. Davidson, C. Fusai

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Scopus)

Abstract

Early recognition of complications following pancreatic surgery could reduce morbidity and mortality. White cell counts (WCCs), platelets (PLTs), C-reactive protein (CRP) and albumin (ALB) are commonly used as guides in clinical decision making. However, the evidence to support their role as early indicators of complications is unclear. A retrospective cohort analysis of consecutive pancreatic surgical procedures between 2004 and 2008 was performed. Operative procedures, inflammatory markers-WCCs, PLTs, CRP, and ALB-preoperatively and on postoperative days (PODs) 1, 3, 5, 7, 9, 12, and 15, and clinical outcomes were recorded. WCC > 11 X 10(9)/L on POD5 was significantly associated with complications [odds ratio (OR), 2.60; P = 0.0067]. ALB 12.2 X 10(9)/L and ALB

Original language	English
Pages (from-to)	215-220
Number of pages	6
Journal	INTERNATIONAL SURGERY
Volume	95
Issue number	3
Publication status	Published - 2010

Keywords

Pancreatic surgery
Complications
Biochemical indicators
SYSTEMIC INFLAMMATORY RESPONSE
SURGICAL SITE INFECTION
C-REACTIVE PROTEIN
POSTOPERATIVE COMPLICATIONS
PROGNOSTIC VALUE
RISK-FACTORS
CANCER
PANCREATICODUODENECTOMY
MORTALITY
MORBIDITY

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@article{bc0eaad3c6914d55b772cf783840593e,

title = "Biochemical Indicators of In-Hospital Complications Following Pancreatic Surgery",

abstract = "Early recognition of complications following pancreatic surgery could reduce morbidity and mortality. White cell counts (WCCs), platelets (PLTs), C-reactive protein (CRP) and albumin (ALB) are commonly used as guides in clinical decision making. However, the evidence to support their role as early indicators of complications is unclear. A retrospective cohort analysis of consecutive pancreatic surgical procedures between 2004 and 2008 was performed. Operative procedures, inflammatory markers-WCCs, PLTs, CRP, and ALB-preoperatively and on postoperative days (PODs) 1, 3, 5, 7, 9, 12, and 15, and clinical outcomes were recorded. WCC > 11 X 10(9)/L on POD5 was significantly associated with complications [odds ratio (OR), 2.60; P = 0.0067]. ALB 12.2 X 10(9)/L and ALB",

keywords = "Pancreatic surgery, Complications, Biochemical indicators, SYSTEMIC INFLAMMATORY RESPONSE, SURGICAL SITE INFECTION, C-REACTIVE PROTEIN, POSTOPERATIVE COMPLICATIONS, PROGNOSTIC VALUE, RISK-FACTORS, CANCER, PANCREATICODUODENECTOMY, MORTALITY, MORBIDITY",

author = "John, {Biku J.} and Sanjay Wijeyekoon and Nienke Warnaar and Prasoona Shasi and Rahman, {Sakirullah H.} and Davidson, {B. R.} and C. Fusai",

year = "2010",

language = "English",

volume = "95",

pages = "215--220",

journal = "INTERNATIONAL SURGERY",

issn = "0020-8868",

number = "3",

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TY - JOUR

T1 - Biochemical Indicators of In-Hospital Complications Following Pancreatic Surgery

AU - John, Biku J.

AU - Wijeyekoon, Sanjay

AU - Warnaar, Nienke

AU - Shasi, Prasoona

AU - Rahman, Sakirullah H.

AU - Davidson, B. R.

AU - Fusai, C.

PY - 2010

Y1 - 2010

N2 - Early recognition of complications following pancreatic surgery could reduce morbidity and mortality. White cell counts (WCCs), platelets (PLTs), C-reactive protein (CRP) and albumin (ALB) are commonly used as guides in clinical decision making. However, the evidence to support their role as early indicators of complications is unclear. A retrospective cohort analysis of consecutive pancreatic surgical procedures between 2004 and 2008 was performed. Operative procedures, inflammatory markers-WCCs, PLTs, CRP, and ALB-preoperatively and on postoperative days (PODs) 1, 3, 5, 7, 9, 12, and 15, and clinical outcomes were recorded. WCC > 11 X 10(9)/L on POD5 was significantly associated with complications [odds ratio (OR), 2.60; P = 0.0067]. ALB 12.2 X 10(9)/L and ALB

AB - Early recognition of complications following pancreatic surgery could reduce morbidity and mortality. White cell counts (WCCs), platelets (PLTs), C-reactive protein (CRP) and albumin (ALB) are commonly used as guides in clinical decision making. However, the evidence to support their role as early indicators of complications is unclear. A retrospective cohort analysis of consecutive pancreatic surgical procedures between 2004 and 2008 was performed. Operative procedures, inflammatory markers-WCCs, PLTs, CRP, and ALB-preoperatively and on postoperative days (PODs) 1, 3, 5, 7, 9, 12, and 15, and clinical outcomes were recorded. WCC > 11 X 10(9)/L on POD5 was significantly associated with complications [odds ratio (OR), 2.60; P = 0.0067]. ALB 12.2 X 10(9)/L and ALB

KW - Pancreatic surgery

KW - Complications

KW - Biochemical indicators

KW - SYSTEMIC INFLAMMATORY RESPONSE

KW - SURGICAL SITE INFECTION

KW - C-REACTIVE PROTEIN

KW - POSTOPERATIVE COMPLICATIONS

KW - PROGNOSTIC VALUE

KW - RISK-FACTORS

KW - CANCER

KW - PANCREATICODUODENECTOMY

KW - MORTALITY

KW - MORBIDITY

M3 - Article

SN - 0020-8868

VL - 95

SP - 215

EP - 220

JO - INTERNATIONAL SURGERY

JF - INTERNATIONAL SURGERY

IS - 3

ER -

Biochemical Indicators of In-Hospital Complications Following Pancreatic Surgery

Abstract

Keywords

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