Biocompatibility of a novel tissue connector for fixation of tracheostoma valves and shunt valves

AA Geertsema*, HK Schutte, MBM van Leeuwen, G Rakhorst, JM Schakenraad, MJA van Luyn, GJ Verkerke

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Abstract

Rehabilitation after laryngectomy often includes the use of a shunt valve and a tracheostoma valve to restore voice. To improve the fixation method of these valves, a new tissue connector has been developed, basically consisting of a ring that will be integrated into surrounding tracheal soft tissue. The valves can be placed in the ring. To test the principle of the tissue connector, a prototype consisting of a subcutaneous polypropylene mesh and a percutaneous titanium stylus was implanted into the backskin of 10 rats by a two-stage surgical procedure. We reasoned that if a firm connection can be realized with the skin, a firm connection with the trachea will also be possible. The subcutaneous part was implanted first, followed by the percutaneous part after 6 weeks. The complete tissue connector with surrounding tissue was removed 8 weeks later and examined histologically. The principle of the new tissue connector proved to be effective: hardly any epithelial downgrowth appeared, and adhesion of soft tissue was demonstrated. No infection or severe inflammation reaction was detected. The tissue connector seems appropriate for its intended use. (C) 1999 Elsevier Science Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)1997-2005
Number of pages9
JournalBiomaterials
Volume20
Issue number21
Publication statusPublished - Nov-1999

Keywords

  • tissue connector
  • percutaneous implants
  • polypropylene mesh
  • titanium
  • two-stage surgical procedure
  • laryngectomy
  • PERCUTANEOUS ACCESS DEVICE
  • TRACHEAL PROSTHESIS
  • PERITONEAL-DIALYSIS
  • IMPLANTS
  • MESH
  • HYDROXYAPATITE
  • EXPERIENCE
  • REPAIR
  • CARBON
  • DESIGN

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