Abstract
We describe 2 sibs, a male fetus with an unusual lumbar hernia and spina bifida occulta, and a female fetus with a median abdominoschisis. The first fetus had some signs of lumbocostovertebral syndrome (LCVS), which consists of a congenital lumbar hernia and associated abnormalities such as absent or hypoplastic ribs, hemivertebrae, and scoliosis, Abdominoschisis has not been described in LCVS, and the given abnormalities in the 2 sibs have not been published to date. One can hypothesize that vascular disruption of a somite or a group of somites may result in the described abdominal wall defects, We conclude that these abnormalities could be coincidental in the 2 sibs or could have a related, probably multifactorial, cause. (C) 1997 Wiley-Liss, Inc.
Original language | English |
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Pages (from-to) | 15-18 |
Number of pages | 4 |
Journal | American Journal of Medical Genetics |
Volume | 73 |
Issue number | 1 |
Publication status | Published - 28-Nov-1997 |
Keywords
- abdominal wall defect
- lumbar hernia
- lumbocostovertebral syndrome
- spina bifida occulta
- autosomal-recessive inheritance
- recurrence risk
- FAMILIAL OMPHALOCELE
- GASTROSCHISIS
- HERNIA
- RISK