Bright morning light advances the human circadian system without affecting NREM sleep homeostasis

Derk Jan Dijk, Domien G.M. Beersma, Serge Daan, Alfred J. Lewy

Research output: Contribution to journalArticleAcademicpeer-review

87 Citations (Scopus)
322 Downloads (Pure)

Abstract

Eight male subjects were exposed to either bright light or dim light between 0600 and 0900 h for 3 consecutive days each. Relative to the dim light condition, the bright light treatment advanced the evening rise in plasma melatonin and the time of sleep termination (sleep onset was held constant) for on average ~1 h. The magnitude of the advance of the plasma melatonin rise was dependent on its phase in dim light. The reduction in sleep duration was at the expense of rapid-eye-movement (REM) sleep. Spectral analysis of the sleep electroencephalogram (EEG) revealed that the advance of the circadian pacemaker did not affect EEG power densities between 0.25 and 15.0 Hz during either non-REM or REM sleep. The data show that shifting the human circadian pacemaker by 1 h does not affect non-REM sleep homeostasis. These findings are in accordance with the predictions of the two-process model of sleep regulation.
Original languageEnglish
Pages (from-to)R106-R111
Number of pages6
JournalThe American Journal of Physiology - Regulatory, Integrative and Comparative Physiology
Volume256
Issue number2
Publication statusPublished - Jan-1989

Keywords

  • two-process model
  • spectral analysis
  • electroencephalogram
  • circadian rhythms
  • melatonin
  • sleep
  • light

Cite this