Buikklachten en neurologische symptomen als vroege manifestatie van longkanker: een uiting van het anti-Hu-syndroom

A N M Wymenga; D J Slebos; J van der Naalt; J W G van Putten; F T M Peters

Buikklachten en neurologische symptomen als vroege manifestatie van longkanker: een uiting van het anti-Hu-syndroom

Translated title of the contribution: Abdominal complaints and neurological symptoms as an early sign of lung cancer: a manifestation of the anti-Hu syndrome

A N M Wymenga, D J Slebos, J van der Naalt, J W G van Putten, F T M Peters

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

659 Downloads (Pure)

Abstract

In two patients, women aged 73 and 46 years, gastrointestinal symptoms were initially not recognised as a paraneoplastic syndrome due to small-cell lung cancer. This led to redundant diagnostics as well as a delay in final diagnosis. The anti-Hu syndrome is characterised by the presence of anti-Hu antibodies and neurological symptoms. About a quarter of the patients with the anti-Hu syndrome will develop gastrointestinal motility disorders in the course of their illness. The primary tumour is usually a small-cell lung cancer. Whereas the presence of anti-Hu antibodies appears to be beneficial for the oncological prognosis, the neurological outcome is less favourable.

Translated title of the contribution	Abdominal complaints and neurological symptoms as an early sign of lung cancer: a manifestation of the anti-Hu syndrome
Original language	Dutch
Pages (from-to)	616-619
Number of pages	4
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	147
Issue number	13
Publication status	Published - 1-Apr-2003

Access to Document

Buikklachten en neurologische symptomen als vroege manifestatie van longkankerFinal publisher's version, 187 KBLicence: Unspecified

https://www.ntvg.nl/artikelen/buikklachten-en-neurologische-symptomen-als-vroege-manifestatie-van-longkanker-een-uitingLicence: Unspecified

Handle.net

Persistent link

Cite this

Wymenga, A. N. M., Slebos, D. J., van der Naalt, J., van Putten, J. W. G., & Peters, F. T. M. (2003). Buikklachten en neurologische symptomen als vroege manifestatie van longkanker: een uiting van het anti-Hu-syndroom. Nederlands Tijdschrift voor Geneeskunde, 147(13), 616-619. https://www.ntvg.nl/artikelen/buikklachten-en-neurologische-symptomen-als-vroege-manifestatie-van-longkanker-een-uiting

@article{1261fbc08bfe4e58965587916e4bf76a,

title = "Buikklachten en neurologische symptomen als vroege manifestatie van longkanker: een uiting van het anti-Hu-syndroom",

abstract = "In two patients, women aged 73 and 46 years, gastrointestinal symptoms were initially not recognised as a paraneoplastic syndrome due to small-cell lung cancer. This led to redundant diagnostics as well as a delay in final diagnosis. The anti-Hu syndrome is characterised by the presence of anti-Hu antibodies and neurological symptoms. About a quarter of the patients with the anti-Hu syndrome will develop gastrointestinal motility disorders in the course of their illness. The primary tumour is usually a small-cell lung cancer. Whereas the presence of anti-Hu antibodies appears to be beneficial for the oncological prognosis, the neurological outcome is less favourable.",

keywords = "Aged, Autoantibodies/analysis, Carcinoma, Small Cell/diagnosis, Diagnosis, Differential, ELAV Proteins, Female, Gastrointestinal Diseases/diagnosis, Gastrointestinal Motility, Humans, Lung Neoplasms/diagnosis, Middle Aged, Nerve Tissue Proteins/immunology, Nervous System Diseases/diagnosis, Paraneoplastic Syndromes/diagnosis, Prognosis, RNA-Binding Proteins/immunology",

author = "Wymenga, {A N M} and Slebos, {D J} and {van der Naalt}, J and {van Putten}, {J W G} and Peters, {F T M}",

year = "2003",

month = apr,

day = "1",

language = "Dutch",

volume = "147",

pages = "616--619",

journal = "Nederlands Tijdschrift voor Geneeskunde",

issn = "0028-2162",

publisher = "NLM (Medline)",

number = "13",

}

Wymenga, ANM, Slebos, DJ , van der Naalt, J, van Putten, JWG & Peters, FTM 2003, 'Buikklachten en neurologische symptomen als vroege manifestatie van longkanker: een uiting van het anti-Hu-syndroom', Nederlands Tijdschrift voor Geneeskunde, vol. 147, no. 13, pp. 616-619. <https://www.ntvg.nl/artikelen/buikklachten-en-neurologische-symptomen-als-vroege-manifestatie-van-longkanker-een-uiting>

TY - JOUR

T1 - Buikklachten en neurologische symptomen als vroege manifestatie van longkanker

T2 - een uiting van het anti-Hu-syndroom

AU - Wymenga, A N M

AU - Slebos, D J

AU - van der Naalt, J

AU - van Putten, J W G

AU - Peters, F T M

PY - 2003/4/1

Y1 - 2003/4/1

N2 - In two patients, women aged 73 and 46 years, gastrointestinal symptoms were initially not recognised as a paraneoplastic syndrome due to small-cell lung cancer. This led to redundant diagnostics as well as a delay in final diagnosis. The anti-Hu syndrome is characterised by the presence of anti-Hu antibodies and neurological symptoms. About a quarter of the patients with the anti-Hu syndrome will develop gastrointestinal motility disorders in the course of their illness. The primary tumour is usually a small-cell lung cancer. Whereas the presence of anti-Hu antibodies appears to be beneficial for the oncological prognosis, the neurological outcome is less favourable.

AB - In two patients, women aged 73 and 46 years, gastrointestinal symptoms were initially not recognised as a paraneoplastic syndrome due to small-cell lung cancer. This led to redundant diagnostics as well as a delay in final diagnosis. The anti-Hu syndrome is characterised by the presence of anti-Hu antibodies and neurological symptoms. About a quarter of the patients with the anti-Hu syndrome will develop gastrointestinal motility disorders in the course of their illness. The primary tumour is usually a small-cell lung cancer. Whereas the presence of anti-Hu antibodies appears to be beneficial for the oncological prognosis, the neurological outcome is less favourable.

KW - Aged

KW - Autoantibodies/analysis

KW - Carcinoma, Small Cell/diagnosis

KW - Diagnosis, Differential

KW - ELAV Proteins

KW - Female

KW - Gastrointestinal Diseases/diagnosis

KW - Gastrointestinal Motility

KW - Humans

KW - Lung Neoplasms/diagnosis

KW - Middle Aged

KW - Nerve Tissue Proteins/immunology

KW - Nervous System Diseases/diagnosis

KW - Paraneoplastic Syndromes/diagnosis

KW - Prognosis

KW - RNA-Binding Proteins/immunology

M3 - Article

C2 - 12701397

SN - 0028-2162

VL - 147

SP - 616

EP - 619

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

IS - 13

ER -

Buikklachten en neurologische symptomen als vroege manifestatie van longkanker: een uiting van het anti-Hu-syndroom

Abstract

Access to Document

Handle.net

Fingerprint

Cite this