Abstract
A 50 year old, healthy man developed a severe bullous allergic reaction after producing coatings. This was probably caused by a proven contact allergy for two compounds he frequently worked with; 1,6-hexanediol diacrylate (HDDA) and glycidyl methacrylate (GMA). Contact allergies to both compounds are not uncommon, but a severe bullous eruption as in this case has, to the best of our knowledge, not been described before. Multiple positive patch test reactions can be explained by the impurity of industrially used acrylates, through which cosensitization can occur. Careful handling of the chemicals and wearing of protective clothing and gloves can prevent sensitization and can provide protection after sensitization.
| Translated title of the contribution | Bullous allergic reaction in the production of coatings |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 444-449 |
| Number of pages | 6 |
| Journal | Nederlands Tijdschrift voor Dermatologie en Venereologie |
| Volume | 23 |
| Issue number | 8 |
| Publication status | Published - 1-Sept-2013 |
Keywords
- 1,6-hexanediol diacrylate
- Acrylates
- Contact allergy
- Glycidyl methacrylate
- Occupational dermatitis
- 1,6 hexanediol diacrylate
- acrylic acid derivative
- glycidylmethacrylate
- unclassified drug
- adult
- article
- bullous skin disease
- case report
- contact allergy
- human
- male
- material coating
- patch test
- protective clothing
- skin allergy
- skin sensitization