TY - JOUR
T1 - Calciumsuppletie bij patiënten met maagzuurremmers
T2 - calciumcitraat of calciumcarbonaat?
AU - de Jonge, H J M Henk-Marijn
AU - Gans, R O B Rijk
AU - Huls, Gerwin
PY - 2012
Y1 - 2012
N2 - Various calcium supplements are available for patients who have an indication for calcium suppletion. American guidelines and UpToDate recommend prescribing calcium citrate to patients who use antacids The rationale for this advice is that water-insoluble calcium carbonate needs acid for adequate absorption. No convincing scientific evidence supporting the advice to prescribe calcium citrate instead of calcium carbonate to patients who also take antacids is available, and therefore deserves further investigation. On the contrary, the fact that calcium carbonate does not need acid in order to be absorbed, has also not been proven. In clinical practise, it appears important that calcium is taken with meals in order to improve its absorption.
AB - Various calcium supplements are available for patients who have an indication for calcium suppletion. American guidelines and UpToDate recommend prescribing calcium citrate to patients who use antacids The rationale for this advice is that water-insoluble calcium carbonate needs acid for adequate absorption. No convincing scientific evidence supporting the advice to prescribe calcium citrate instead of calcium carbonate to patients who also take antacids is available, and therefore deserves further investigation. On the contrary, the fact that calcium carbonate does not need acid in order to be absorbed, has also not been proven. In clinical practise, it appears important that calcium is taken with meals in order to improve its absorption.
KW - Antacids/adverse effects
KW - Biological Availability
KW - Calcium Carbonate/administration & dosage
KW - Calcium Citrate/administration & dosage
KW - Calcium, Dietary/administration & dosage
KW - Dietary Supplements
KW - Humans
KW - Intestinal Absorption
UR - https://www.ntvg.nl/artikelen/calciumsuppletie-bij-pati%C3%ABnten-met-maagzuurremmers
M3 - Review article
C2 - 22914054
VL - 156
SP - A4343
JO - Nederlands Tijdschrift voor Geneeskunde
JF - Nederlands Tijdschrift voor Geneeskunde
SN - 0028-2162
IS - 34
ER -