Carcinoid in a horseshoe kidney - Morphology, immunohistochemistry, and cytogenetics

E vandenBerg*, ASH Gouw, S Storkel, T Dijkhuizen, HJA Mensink, B deJong

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)

Abstract

Renal carcinoids are very rare neoplasms. We were able to culture and subsequently karyotype a carcinoid located in the isthmus of a horseshoe kidney, which revealed the following chromosomal pattern: 47,XX, + 13[8]/46,XX,t(13;14) (q31;q11.2)[5]/46,XX[2]. The DNA index was 1. Our results, compared with the sparse data from the literature, suggest that carcinoid of the kidney has no cytogenetic aberrations in common with carcinoids from other anatomical sites reported. On the other hand, numerical and structural aberrations of chromosome 13 seem to play a crucial role in the development of metanephric-derived renal tumors.

Original languageEnglish
Pages (from-to)95-98
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume84
Issue number2
Publication statusPublished - 15-Oct-1995

Keywords

  • WILMS-TUMOR

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