CD40-CD40L interactions in atherosclerosis

Jon D. Laman*, Marjan Van Meurs, Bart J.G.L. De Smet, Arjan Schoneveld

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

87 Citations (Scopus)
21 Downloads (Pure)

Abstract

The abundant presence of macrophages and activated T cells in atherosclerotic plaques suggests an active involvement of the immune system in this cardiovascular disease. However, insight into cellular interactions inducing relevant effector functions is still limited. Here, Jon Laman and colleagues propose that local interactions between CD40 and CD40 ligand may induce multiple activities by different cell types contributing to atherosclerosis.

Original languageEnglish
Pages (from-to)272-277
Number of pages6
JournalImmunology Today
Volume18
Issue number6
DOIs
Publication statusPublished - Jun-1997
Externally publishedYes

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