Chemistry and Biology of SARS-CoV-2

Alexander Dömling*, Li Gao

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

36 Citations (Scopus)


Challenges and opportunities: • The SARS-CoV-2 pandemic has changed our world in just half a year: a large number of people have died from the virus-induced pneumonia COVID-19, and the global economy is at an unprecedented low with unknown near- and long-term consequences. • The coronavirus pandemic needs a two-pronged approach: a short-term solution to find a drug to treat the massive number of seriously ill patients, and long-term development of preventive and curative drugs for future corona outbreaks. • De novo drug discovery takes years to move from idea and/or pre-clinic to market release and is not a short-term solution for the current SARS-CoV-2 pandemic. Drug repurposing is perhaps the only short-term solution, and vaccination is a middle-term solution.

Original languageEnglish
Pages (from-to)1283-1295
Number of pages13
Issue number6
Publication statusPublished - 11-Jun-2020

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