Chiral diethanolamines and their lithium alcoholates as catalysts in the enantioselective alkylation of benzaldehyde by diethylzinc

E.F.J. De Vries; J. Brussee; Chris G. Knise; A. Van Der Gen

doi:10.1016/S0957-4166(00)82246-6

Chiral diethanolamines and their lithium alcoholates as catalysts in the enantioselective alkylation of benzaldehyde by diethylzinc

E.F.J. De Vries, J. Brussee, Chris G. Knise, A. Van Der Gen

Faculty of Medical Sciences/UMCG

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Abstract

The enantioselective alkylation of benzaldehyde by diethylzinc in the presence of catalytic amounts of bis-erythro diethanolamines and their lithium alcoholates was studied. The extent of asymmetric induction was found to depend strongly upon subtle changes in the structure of the catalyst used.

Original language	English
Pages (from-to)	1987-1990
Number of pages	4
Journal	Tetrahedron Asymmetry
Volume	4
Issue number	9
DOIs	https://doi.org/10.1016/S0957-4166(00)82246-6
Publication status	Published - 5-Nov-1993

Keywords

benzaldehyde derivative
alkylation
article
catalysis
enantiomer
reaction analysis
stereochemistry
synthesis

Access to Document

10.1016/S0957-4166(00)82246-6

Handle.net

Persistent link

Cite this

@article{c0e79f0b41f44497b0447522d14955cd,

title = "Chiral diethanolamines and their lithium alcoholates as catalysts in the enantioselective alkylation of benzaldehyde by diethylzinc",

abstract = "The enantioselective alkylation of benzaldehyde by diethylzinc in the presence of catalytic amounts of bis-erythro diethanolamines and their lithium alcoholates was studied. The extent of asymmetric induction was found to depend strongly upon subtle changes in the structure of the catalyst used.",

keywords = "benzaldehyde derivative, alkylation, article, catalysis, enantiomer, reaction analysis, stereochemistry, synthesis",

author = "{De Vries}, E.F.J. and J. Brussee and Knise, {Chris G.} and {Van Der Gen}, A.",

year = "1993",

month = nov,

day = "5",

doi = "10.1016/S0957-4166(00)82246-6",

language = "English",

volume = "4",

pages = "1987--1990",

journal = "Tetrahedron Asymmetry",

issn = "0957-4166",

publisher = "PERGAMON-ELSEVIER SCIENCE LTD",

number = "9",

}

TY - JOUR

T1 - Chiral diethanolamines and their lithium alcoholates as catalysts in the enantioselective alkylation of benzaldehyde by diethylzinc

AU - De Vries, E.F.J.

AU - Brussee, J.

AU - Knise, Chris G.

AU - Van Der Gen, A.

PY - 1993/11/5

Y1 - 1993/11/5

N2 - The enantioselective alkylation of benzaldehyde by diethylzinc in the presence of catalytic amounts of bis-erythro diethanolamines and their lithium alcoholates was studied. The extent of asymmetric induction was found to depend strongly upon subtle changes in the structure of the catalyst used.

AB - The enantioselective alkylation of benzaldehyde by diethylzinc in the presence of catalytic amounts of bis-erythro diethanolamines and their lithium alcoholates was studied. The extent of asymmetric induction was found to depend strongly upon subtle changes in the structure of the catalyst used.

KW - benzaldehyde derivative

KW - alkylation

KW - article

KW - catalysis

KW - enantiomer

KW - reaction analysis

KW - stereochemistry

KW - synthesis

U2 - 10.1016/S0957-4166(00)82246-6

DO - 10.1016/S0957-4166(00)82246-6

M3 - Article

SN - 0957-4166

VL - 4

SP - 1987

EP - 1990

JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

IS - 9

ER -

Chiral diethanolamines and their lithium alcoholates as catalysts in the enantioselective alkylation of benzaldehyde by diethylzinc

Abstract

Keywords

Access to Document

Handle.net

Fingerprint

Cite this