Chromanol compounds for treatment of heart failure

Robert Henk Henning (Inventor), Adrianus Cornelis van der Graaf (Inventor), Guido Krenning (Inventor), Lucas Moritz Wiggenhauser (Inventor)

Research output: Patent

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Abstract

The invention relates to certain chromanol, quinone or hydroquinone compounds and derivatives thereof for treatment of heart failure with reduced ejection fraction (HFrEF). Specifically, the present invention relates to chromanol compounds chosen from S-(6-hydroxy-2,5,7,8-tetramethylchroman-2yl)(piperazin-1-yl)methanone and S-(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(4-(2-hydroxyethyl)piperazin-1-yl)methanone, and pharmaceutically acceptable salts thereof.
Original languageEnglish
Patent numberWO2022058620
Priority date21/09/2020
Filing date21/09/2021
Publication statusPublished - 24-Mar-2022

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