Clinical characteristics of subsequent histologically confirmed meningiomas in long-term childhood cancer survivors: A Dutch LATER study

Dutch LATER Study Grp, Lisanne C. Verbruggen*, Judith L. Kok, Jop C. Teepen, Geert O. Janssens, Charlotte M. de Boer, Lukas J. A. Stalpers, Meike W. Vernooij, Eline van Dulmen-den Broeder, Jacqueline J. Loonen, Marry M. van den Heuvel-Eibrink, Wim J. E. Tissing, Margriet van der van der Loo, Anne Birgitta Versluys, Sebastian J. C. M. M. Neggers, Flora E. van Leeuwen, Eelco W. Hoving, Pieter Wesseling, Leontine C. M. Kremer, Cecile M. RonckersHelena J. H. van der Pal

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Background: Meningiomas are the most frequent brain tumours occurring after pediatric cranial radiotherapy (CrRT). Data on course of disease, to inform clinical management of meningiomas, are sparse. This study reports the clinical characteristics of histologically confirmed meningiomas in childhood cancer survivors (CCS) in the Netherlands.& nbsp; Methods: In total, 6015 CCS from the Dutch Long-Term Effects After Childhood Cancer (LATER) cohort were eligible, including 1551 with prior CrRT. These CCS were diagnosed with cancer age

Original languageEnglish
Pages (from-to)240-249
Number of pages10
JournalEuropean Journal of Cancer
Volume150
Early online date30-Apr-2021
DOIs
Publication statusPublished - Jun-2021

Keywords

  • Subsequent meningioma
  • Childhood adolescent young adult (CAYA) cancer survivors
  • Cranial radiotherapy
  • CENTRAL-NERVOUS-SYSTEM
  • RADIATION-INDUCED MENINGIOMAS
  • MULTIPLE MENINGIOMAS
  • CRANIAL RADIOTHERAPY
  • NEOPLASMS
  • TUMORS
  • CLASSIFICATION
  • BRAIN
  • RISK
  • LIFE

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