Clinical implementations of 4D pencil beam scanned particle therapy: Report on the 4D treatment planning workshop 2016 and 2017

Petra Trnkova; Barbara Knaeusl; Oxana Actis; Christoph Bert; Aleksandra K. Biegun; Till T. Boehlen; Hugo Furtado; Jamie McClelland; Shinichiro Mori; Ilaria Rinaldi; Antoni Rucinski; Antje C. Knopf

doi:10.1016/j.ejmp.2018.10.002

Clinical implementations of 4D pencil beam scanned particle therapy: Report on the 4D treatment planning workshop 2016 and 2017

Petra Trnkova, Barbara Knaeusl, Oxana Actis, Christoph Bert, Aleksandra K. Biegun, Till T. Boehlen, Hugo Furtado, Jamie McClelland, Shinichiro Mori, Ilaria Rinaldi, Antoni Rucinski, Antje C. Knopf^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

In 2016 and 2017, the 8th and 9th 4D treatment planning workshop took place in Groningen (the Netherlands) and Vienna (Austria), respectively. This annual workshop brings together international experts to discuss research, advances in clinical implementation as well as problems and challenges in 4D treatment planning, mainly in spot scanned proton therapy. In the last two years several aspects like treatment planning, beam delivery, Monte Carlo simulations, motion modeling and monitoring, QA phantoms as well as 4D imaging were thoroughly discussed.

This report provides an overview of discussed topics, recent findings and literature review from the last two years. Its main focus is to highlight translation of 4D research into clinical practice and to discuss remaining challenges and pitfalls that still need to be addressed and to be overcome.

Original language	English
Pages (from-to)	121-130
Number of pages	10
Journal	Physica medica-European journal of medical physics
Volume	54
DOIs	https://doi.org/10.1016/j.ejmp.2018.10.002
Publication status	Published - Oct-2018

Keywords

Proton therapy
Moving targets
4D imaging
4D dosimetry
MODULATED PROTON THERAPY
DYNAMIC MLC TRACKING
CONVOLUTIONAL NEURAL-NETWORK
RESPIRATORY MOTION MODELS
MONTE-CARLO CODE
LUNG-CANCER
DOSE CALCULATION
RADIATION-THERAPY
QUALITY-ASSURANCE
MAGNETIC-FIELD

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Trnkova, P., Knaeusl, B., Actis, O., Bert, C., Biegun, A. K., Boehlen, T. T., Furtado, H., McClelland, J., Mori, S., Rinaldi, I., Rucinski, A., & Knopf, A. C. (2018). Clinical implementations of 4D pencil beam scanned particle therapy: Report on the 4D treatment planning workshop 2016 and 2017. Physica medica-European journal of medical physics, 54, 121-130. https://doi.org/10.1016/j.ejmp.2018.10.002

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title = "Clinical implementations of 4D pencil beam scanned particle therapy: Report on the 4D treatment planning workshop 2016 and 2017",

abstract = "In 2016 and 2017, the 8th and 9th 4D treatment planning workshop took place in Groningen (the Netherlands) and Vienna (Austria), respectively. This annual workshop brings together international experts to discuss research, advances in clinical implementation as well as problems and challenges in 4D treatment planning, mainly in spot scanned proton therapy. In the last two years several aspects like treatment planning, beam delivery, Monte Carlo simulations, motion modeling and monitoring, QA phantoms as well as 4D imaging were thoroughly discussed.This report provides an overview of discussed topics, recent findings and literature review from the last two years. Its main focus is to highlight translation of 4D research into clinical practice and to discuss remaining challenges and pitfalls that still need to be addressed and to be overcome.",

keywords = "Proton therapy, Moving targets, 4D imaging, 4D dosimetry, MODULATED PROTON THERAPY, DYNAMIC MLC TRACKING, CONVOLUTIONAL NEURAL-NETWORK, RESPIRATORY MOTION MODELS, MONTE-CARLO CODE, LUNG-CANCER, DOSE CALCULATION, RADIATION-THERAPY, QUALITY-ASSURANCE, MAGNETIC-FIELD",

author = "Petra Trnkova and Barbara Knaeusl and Oxana Actis and Christoph Bert and Biegun, {Aleksandra K.} and Boehlen, {Till T.} and Hugo Furtado and Jamie McClelland and Shinichiro Mori and Ilaria Rinaldi and Antoni Rucinski and Knopf, {Antje C.}",

year = "2018",

month = oct,

doi = "10.1016/j.ejmp.2018.10.002",

language = "English",

volume = "54",

pages = "121--130",

journal = "Physica medica-European journal of medical physics",

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Trnkova, P, Knaeusl, B, Actis, O, Bert, C, Biegun, AK, Boehlen, TT, Furtado, H, McClelland, J, Mori, S, Rinaldi, I, Rucinski, A & Knopf, AC 2018, 'Clinical implementations of 4D pencil beam scanned particle therapy: Report on the 4D treatment planning workshop 2016 and 2017', Physica medica-European journal of medical physics, vol. 54, pp. 121-130. https://doi.org/10.1016/j.ejmp.2018.10.002

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AU - Trnkova, Petra

AU - Knaeusl, Barbara

AU - Actis, Oxana

AU - Bert, Christoph

AU - Biegun, Aleksandra K.

AU - Boehlen, Till T.

AU - Furtado, Hugo

AU - McClelland, Jamie

AU - Mori, Shinichiro

AU - Rinaldi, Ilaria

AU - Rucinski, Antoni

AU - Knopf, Antje C.

PY - 2018/10

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N2 - In 2016 and 2017, the 8th and 9th 4D treatment planning workshop took place in Groningen (the Netherlands) and Vienna (Austria), respectively. This annual workshop brings together international experts to discuss research, advances in clinical implementation as well as problems and challenges in 4D treatment planning, mainly in spot scanned proton therapy. In the last two years several aspects like treatment planning, beam delivery, Monte Carlo simulations, motion modeling and monitoring, QA phantoms as well as 4D imaging were thoroughly discussed.This report provides an overview of discussed topics, recent findings and literature review from the last two years. Its main focus is to highlight translation of 4D research into clinical practice and to discuss remaining challenges and pitfalls that still need to be addressed and to be overcome.

AB - In 2016 and 2017, the 8th and 9th 4D treatment planning workshop took place in Groningen (the Netherlands) and Vienna (Austria), respectively. This annual workshop brings together international experts to discuss research, advances in clinical implementation as well as problems and challenges in 4D treatment planning, mainly in spot scanned proton therapy. In the last two years several aspects like treatment planning, beam delivery, Monte Carlo simulations, motion modeling and monitoring, QA phantoms as well as 4D imaging were thoroughly discussed.This report provides an overview of discussed topics, recent findings and literature review from the last two years. Its main focus is to highlight translation of 4D research into clinical practice and to discuss remaining challenges and pitfalls that still need to be addressed and to be overcome.

KW - Proton therapy

KW - Moving targets

KW - 4D imaging

KW - 4D dosimetry

KW - MODULATED PROTON THERAPY

KW - DYNAMIC MLC TRACKING

KW - CONVOLUTIONAL NEURAL-NETWORK

KW - RESPIRATORY MOTION MODELS

KW - MONTE-CARLO CODE

KW - LUNG-CANCER

KW - DOSE CALCULATION

KW - RADIATION-THERAPY

KW - QUALITY-ASSURANCE

KW - MAGNETIC-FIELD

U2 - 10.1016/j.ejmp.2018.10.002

DO - 10.1016/j.ejmp.2018.10.002

M3 - Article

SN - 1120-1797

VL - 54

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EP - 130

JO - Physica medica-European journal of medical physics

JF - Physica medica-European journal of medical physics

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