Abstract

Treatment choice in elderly pharyngeal cancer patient is disputed. This study was aimed to asses association of co-morbidity, complications and survival in different treatment modalities of pharyngeal cancer patients.

Retrospective analysis of pharyngeal cancer patients, diagnosed between 1997 and 2007 in a tertiary referral hospital was performed. Patients 75 years and older (n = 42), were matched with two control patients 64 years and younger (n = 84). Co-morbidity (ACE-27), treatment related complications and survival data were assessed and analyzed.

Frequency of co-morbidity was similar in both age groups, although discarding alcohol abuse resulted in higher incidence of co-morbidity in the elderly group. Complication rate was not significantly different. In a multivariate analysis only stage found to be a significant predictor of complications. Survival estimates adjusted to sex, age and birth cohort revealed co-morbidity to be a significant predictor for survival in elderly and young patients.

No evidence has been found to treat elderly pharyngeal cancer patients differently than younger ones. Treatment related complications are not predicted by co-morbidities in young and elderly patients; however survival is predicted by comorbidity. Therefore thorough pre-treatment evaluation and care necessary in the elderly population. (C) 2011 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)1159-1164
Number of pages6
JournalOral Oncology
Volume47
Issue number12
DOIs
Publication statusPublished - Dec-2011

Keywords

  • Pharyngeal cancer
  • Elderly
  • Co-morbidity
  • Complication
  • Survival
  • NECK-CANCER
  • PERIOPERATIVE COMPLICATIONS
  • OROPHARYNGEAL CANCER
  • MAJOR HEAD
  • COMORBIDITY
  • SURGERY
  • RECONSTRUCTION
  • CARCINOMA
  • SURVIVAL
  • AGE

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