Consensus recommendations on altered sensory functioning in Phelan-McDermid syndrome

the European Phelan-McDermid syndrome consortium, Margreet Walinga*, Sarah Jesse, Norma Alhambra, Griet Van Buggenhout

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)
99 Downloads (Pure)

Abstract

Altered sensory functioning is often observed in individuals with SHANK3 related Phelan-McDermid syndrome (PMS). Compared to typically developing individuals and individuals with an autism spectrum disorder, it has been suggested that there are distinctive features of sensory functioning in PMS. More hyporeactivity symptoms and less hyperreactivity and sensory seeking behaviour are seen, particularly in the auditory domain. Hypersensitivity to touch, possible overheating or turning red easily and reduced pain response are often seen. In this paper the current literature on sensory functioning in PMS is reviewed and recommendations for caregivers, based on consensus within the European PMS consortium, are given.

Original languageEnglish
Article number104726
Number of pages5
JournalEuropean journal of medical genetics
Volume66
Issue number5
DOIs
Publication statusPublished - May-2023

Keywords

  • Guideline
  • Pain
  • Phelan-McDermid syndrome
  • Sensory dysfunction
  • Sensory processing disorder
  • SHANK3

Fingerprint

Dive into the research topics of 'Consensus recommendations on altered sensory functioning in Phelan-McDermid syndrome'. Together they form a unique fingerprint.

Cite this