CONTEMPORARY MANAGEMENT OF SINONASAL CANCER

K. Thomas Robbins, Alfio Ferlito*, Carl E. Silver, Robert P. Takes, Primoz Strojan, Carl H. Snyderman, Remco de Bree, Missak Haigentz, Johannes A. Langendijk, Alessandra Rinaldo, Ashok R. Shaha, Ehab Y. Hanna, Jochen A. Werner, Carlos Suarez

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

46 Citations (Scopus)

Abstract

Background. Sinonasal cancer is a relatively uncommon entity encountered by head and neck oncologists, rhinologists, and skull base surgeons. Recent innovations in surgical and nonsurgical therapeutic modalities raise the question of whether there has been any measurable improvement for treatment outcomes.

Methods. A retrospective review of data from recent studies that focus on surgery, radiation, and chemotherapy, or combinations thereof, was conducted.

Results. Surgery continues to be the preferred treatment and provides the best results, albeit with an inherent bias based on patient selection. For advanced disease (T4 lesions), the survival rate remains only modest. Complications of treatment, including both surgical and radiation therapy, have been reduced.

Conclusions. There is a need to improve the efficacy of treatment for this disease. Recommendations for the future direction of therapeutic investigations are outlined. (C) 2010 Wiley Periodicals, Inc. Head Neck 33: 1352-1365, 2011

Original languageEnglish
Pages (from-to)1352-1365
Number of pages14
JournalHead and Neck: Journal of the Sciences and Specialties of the Head and Neck
Volume33
Issue number9
DOIs
Publication statusPublished - Sep-2011

Keywords

  • sinonasal cancer
  • treatment
  • endoscopic surgical resection
  • radiation therapy
  • chemotherapy
  • quality of life
  • PARANASAL SINUS CARCINOMA
  • ADENOID CYSTIC CARCINOMA
  • 3-DIMENSIONAL CONFORMAL RADIOTHERAPY
  • SINGLE INSTITUTION EXPERIENCE
  • SQUAMOUS-CELL CARCINOMA
  • ANTERIOR SKULL BASE
  • QUALITY-OF-LIFE
  • MAXILLARY SINUS
  • NASAL CAVITY
  • NECK-CANCER

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