Context-dependent Dynamic Processes in Attention Deficit/Hyperactivity Disorder: Differentiating Common and Unique Effects of State Regulation Deficits and Delay Aversion

Edmund J. S. Sonuga-Barke*, Jan R. Wiersema, Jacob J. van der Meere, Herbert Roeyers

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

68 Citations (Scopus)

Abstract

The ability to specify differential predictions is a mark of a scientific models' value. State regulation deficits (SRD) and delay aversion (DAv) have both been hypothesized as context-dependent dynamic dysfunctions in ADHD. However, to date there has been no systematic comparison of their common and unique elements. Here we review these hypotheses-and describe the core and secondary manifestations of the two constructs and review evidence in support of them. Second, we focus on what are seen as the hallmark indicators of the two deficits-preference of small immediate over large delayed rewards for DAv and the slow event rate effect for SRD. We describe the overlap between these two manifestations and then explore how experimental manipulations and the analysis of neuropsychological and physiological mediators of effects can allow us to differentiate these two patterns of neuropsychological dysfunction on the basis of specific predictions. Finally, we highlight the implications of neuropsychological heterogeneity for the practical implementation of tests of DAv and SRD.

Original languageEnglish
Pages (from-to)86-102
Number of pages17
JournalNeuropsychology Review
Volume20
Issue number1
DOIs
Publication statusPublished - Mar-2010

Keywords

  • Attention deficit/hyperactivity disorder
  • Delay aversion
  • State regulation
  • Cognitive energetic
  • Event rate
  • Delay of gratification
  • Delayed reward
  • STRIATAL DOPAMINE RELEASE
  • DUAL PATHWAY MODEL
  • HYPERACTIVITY DISORDER
  • RESPONSE-INHIBITION
  • WORKING-MEMORY
  • SUSTAINED ATTENTION
  • DECISION-MAKING
  • ADHD CHILDREN
  • EVENT RATE
  • EXECUTIVE DYSFUNCTION

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