Cortico-thalamic activation in generalized status epilepticus, a PET study

B. M. de Jong*, J. H. van de Hoeven, J. Pruim, J. van der Naalt, John H. J. M. Meertens

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Abstract

In a patient with a refractory generalized convulsive status epilepticus, the ictal distribution of regional cerebral glucose was assessed with positron emission tomography (PET). Synchronized seizure activity in the EEG was associated with bilateral metabolic activation of medial sensorimotor regions, anterior cingulate, cortex, striatum and thalamus. This pattern with focal cortical activation supports the concept that a cortical focus may drive epilepsy, while the thalamus mediates synchronization of neuronal activity as reflected in the EEG. (C) 2007 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)182-185
Number of pages4
JournalClinical neurology and neurosurgery
Volume110
Issue number2
DOIs
Publication statusPublished - Feb-2008

Keywords

  • generalized status epilepticus
  • ictal PET
  • FDG
  • cingulate gyrus
  • POSITRON-EMISSION-TOMOGRAPHY
  • ABSENCE SEIZURES
  • CHILDREN

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