Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospital

Jan-Willem H. Dik; Ron Hendrix; Alex W. Friedrich; Jos Luttjeboer; Prashant Nannan Panday; Kasper R. Wilting; Jerome R. Lo-Ten-Foe; Maarten J. Postma; Bhanu Sinha

doi:10.1371/journal.pone.0126106

Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospital

Jan-Willem H. Dik, Ron Hendrix, Alex W. Friedrich^*, Jos Luttjeboer, Prashant Nannan Panday, Kasper R. Wilting, Jerome R. Lo-Ten-Foe, Maarten J. Postma, Bhanu Sinha

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

397 Downloads (Pure)

Abstract

Background

In order to stimulate appropriate antimicrobial use and thereby lower the chances of resistance development, an Antibiotic Stewardship Team (A-Team) has been implemented at the University Medical Center Groningen, the Netherlands. Focus of the A-Team was a pro-active day 2 case-audit, which was financially evaluated here to calculate the return on investment from a hospital perspective.

Methods

Effects were evaluated by comparing audited patients with a historic cohort with the same diagnosis-related groups. Based upon this evaluation a cost-minimization model was created that can be used to predict the financial effects of a day 2 case-audit. Sensitivity analyses were performed to deal with uncertainties. Finally, the model was used to financially evaluate the A-Team.

Results

One whole year including 114 patients was evaluated. Implementation costs were calculated to be (sic)17,732, which represent total costs spent to implement this A-Team. For this specific patient group admitted to a urology ward and consulted on day 2 by the A-Team, the model estimated total savings of (sic)60,306 after one year for this single department, leading to a return on investment of 5.9.

Conclusions

The implemented multi-disciplinary A-Team performing a day 2 case-audit in the hospital had a positive return on investment caused by a reduced length of stay due to a more appropriate antibiotic therapy. Based on the extensive data analysis, a model of this intervention could be constructed. This model could be used by other institutions, using their own data to estimate the effects of a day 2 case-audit in their hospital.

Original language	English
Article number	e0126106
Number of pages	12
Journal	PLoS ONE
Volume	10
Issue number	5
DOIs	https://doi.org/10.1371/journal.pone.0126106
Publication status	Published - 8-May-2015

Keywords

ANTIMICROBIAL STEWARDSHIP
HEALTH-CARE
ECONOMIC OUTCOMES
PROGRAM
INFECTIONS
INTERVENTION
PREVENTION
GUIDELINES
MANAGEMENT
RESISTANCE

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Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospitaFinal publisher's version, 518 KBLicence: CC BY

Data from: Cost-minimization model of a multidisciplinary antibiotic stewardship team based on a successful implementation on a urology ward of an academic hospital
Dik, J. (Creator), Hendrix, R. (Creator), Friedrich, A. (Creator), Luttjeboer, J. (Creator), Nannan Panday, P. (Creator), Wilting, K. R. (Creator), Lo-Ten-Foe, J. R. (Creator), Postma, M. (Creator) & Sinha, B. (Creator), University of Groningen, 8-May-2015
DOI: 10.5061/dryad.kq2r1
Dataset

Cite this

Dik, J-W. H., Hendrix, R., Friedrich, A. W., Luttjeboer, J., Panday, P. N., Wilting, K. R., Lo-Ten-Foe, J. R., Postma, M. J., & Sinha, B. (2015). Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospital. PLoS ONE, 10(5), [e0126106]. https://doi.org/10.1371/journal.pone.0126106

Dik, Jan-Willem H. ; Hendrix, Ron ; Friedrich, Alex W. ; Luttjeboer, Jos ; Panday, Prashant Nannan ; Wilting, Kasper R. ; Lo-Ten-Foe, Jerome R. ; Postma, Maarten J. ; Sinha, Bhanu. / Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospital. In: PLoS ONE. 2015 ; Vol. 10, No. 5.

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title = "Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospital",

abstract = "BackgroundIn order to stimulate appropriate antimicrobial use and thereby lower the chances of resistance development, an Antibiotic Stewardship Team (A-Team) has been implemented at the University Medical Center Groningen, the Netherlands. Focus of the A-Team was a pro-active day 2 case-audit, which was financially evaluated here to calculate the return on investment from a hospital perspective.MethodsEffects were evaluated by comparing audited patients with a historic cohort with the same diagnosis-related groups. Based upon this evaluation a cost-minimization model was created that can be used to predict the financial effects of a day 2 case-audit. Sensitivity analyses were performed to deal with uncertainties. Finally, the model was used to financially evaluate the A-Team.ResultsOne whole year including 114 patients was evaluated. Implementation costs were calculated to be (sic)17,732, which represent total costs spent to implement this A-Team. For this specific patient group admitted to a urology ward and consulted on day 2 by the A-Team, the model estimated total savings of (sic)60,306 after one year for this single department, leading to a return on investment of 5.9.ConclusionsThe implemented multi-disciplinary A-Team performing a day 2 case-audit in the hospital had a positive return on investment caused by a reduced length of stay due to a more appropriate antibiotic therapy. Based on the extensive data analysis, a model of this intervention could be constructed. This model could be used by other institutions, using their own data to estimate the effects of a day 2 case-audit in their hospital.",

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author = "Dik, {Jan-Willem H.} and Ron Hendrix and Friedrich, {Alex W.} and Jos Luttjeboer and Panday, {Prashant Nannan} and Wilting, {Kasper R.} and Lo-Ten-Foe, {Jerome R.} and Postma, {Maarten J.} and Bhanu Sinha",

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Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospital. / Dik, Jan-Willem H.; Hendrix, Ron ; Friedrich, Alex W.; Luttjeboer, Jos ; Panday, Prashant Nannan; Wilting, Kasper R.; Lo-Ten-Foe, Jerome R.; Postma, Maarten J.; Sinha, Bhanu.

In: PLoS ONE, Vol. 10, No. 5, e0126106, 08.05.2015.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospital

AU - Dik, Jan-Willem H.

AU - Hendrix, Ron

AU - Friedrich, Alex W.

AU - Luttjeboer, Jos

AU - Panday, Prashant Nannan

AU - Wilting, Kasper R.

AU - Lo-Ten-Foe, Jerome R.

AU - Postma, Maarten J.

AU - Sinha, Bhanu

PY - 2015/5/8

Y1 - 2015/5/8

N2 - BackgroundIn order to stimulate appropriate antimicrobial use and thereby lower the chances of resistance development, an Antibiotic Stewardship Team (A-Team) has been implemented at the University Medical Center Groningen, the Netherlands. Focus of the A-Team was a pro-active day 2 case-audit, which was financially evaluated here to calculate the return on investment from a hospital perspective.MethodsEffects were evaluated by comparing audited patients with a historic cohort with the same diagnosis-related groups. Based upon this evaluation a cost-minimization model was created that can be used to predict the financial effects of a day 2 case-audit. Sensitivity analyses were performed to deal with uncertainties. Finally, the model was used to financially evaluate the A-Team.ResultsOne whole year including 114 patients was evaluated. Implementation costs were calculated to be (sic)17,732, which represent total costs spent to implement this A-Team. For this specific patient group admitted to a urology ward and consulted on day 2 by the A-Team, the model estimated total savings of (sic)60,306 after one year for this single department, leading to a return on investment of 5.9.ConclusionsThe implemented multi-disciplinary A-Team performing a day 2 case-audit in the hospital had a positive return on investment caused by a reduced length of stay due to a more appropriate antibiotic therapy. Based on the extensive data analysis, a model of this intervention could be constructed. This model could be used by other institutions, using their own data to estimate the effects of a day 2 case-audit in their hospital.

AB - BackgroundIn order to stimulate appropriate antimicrobial use and thereby lower the chances of resistance development, an Antibiotic Stewardship Team (A-Team) has been implemented at the University Medical Center Groningen, the Netherlands. Focus of the A-Team was a pro-active day 2 case-audit, which was financially evaluated here to calculate the return on investment from a hospital perspective.MethodsEffects were evaluated by comparing audited patients with a historic cohort with the same diagnosis-related groups. Based upon this evaluation a cost-minimization model was created that can be used to predict the financial effects of a day 2 case-audit. Sensitivity analyses were performed to deal with uncertainties. Finally, the model was used to financially evaluate the A-Team.ResultsOne whole year including 114 patients was evaluated. Implementation costs were calculated to be (sic)17,732, which represent total costs spent to implement this A-Team. For this specific patient group admitted to a urology ward and consulted on day 2 by the A-Team, the model estimated total savings of (sic)60,306 after one year for this single department, leading to a return on investment of 5.9.ConclusionsThe implemented multi-disciplinary A-Team performing a day 2 case-audit in the hospital had a positive return on investment caused by a reduced length of stay due to a more appropriate antibiotic therapy. Based on the extensive data analysis, a model of this intervention could be constructed. This model could be used by other institutions, using their own data to estimate the effects of a day 2 case-audit in their hospital.

KW - ANTIMICROBIAL STEWARDSHIP

KW - HEALTH-CARE

KW - ECONOMIC OUTCOMES

KW - PROGRAM

KW - INFECTIONS

KW - INTERVENTION

KW - PREVENTION

KW - GUIDELINES

KW - MANAGEMENT

KW - RESISTANCE

U2 - 10.1371/journal.pone.0126106

DO - 10.1371/journal.pone.0126106

M3 - Article

C2 - 25955494

VL - 10

JO - PLOS-One

JF - PLOS-One

SN - 1932-6203

IS - 5

M1 - e0126106

ER -

Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospital

Abstract

Keywords

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Data from: Cost-minimization model of a multidisciplinary antibiotic stewardship team based on a successful implementation on a urology ward of an academic hospital

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