Cost-minimization model of a multidisciplinary Antibiotic Stewardship Team based on a successful implementation on a urology ward of an academic hospital

Jan-Willem H. Dik, Ron Hendrix, Alex W. Friedrich*, Jos Luttjeboer, Prashant Nannan Panday, Kasper R. Wilting, Jerome R. Lo-Ten-Foe, Maarten J. Postma, Bhanu Sinha

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)
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Abstract

Background

In order to stimulate appropriate antimicrobial use and thereby lower the chances of resistance development, an Antibiotic Stewardship Team (A-Team) has been implemented at the University Medical Center Groningen, the Netherlands. Focus of the A-Team was a pro-active day 2 case-audit, which was financially evaluated here to calculate the return on investment from a hospital perspective.

Methods

Effects were evaluated by comparing audited patients with a historic cohort with the same diagnosis-related groups. Based upon this evaluation a cost-minimization model was created that can be used to predict the financial effects of a day 2 case-audit. Sensitivity analyses were performed to deal with uncertainties. Finally, the model was used to financially evaluate the A-Team.

Results

One whole year including 114 patients was evaluated. Implementation costs were calculated to be (sic)17,732, which represent total costs spent to implement this A-Team. For this specific patient group admitted to a urology ward and consulted on day 2 by the A-Team, the model estimated total savings of (sic)60,306 after one year for this single department, leading to a return on investment of 5.9.

Conclusions

The implemented multi-disciplinary A-Team performing a day 2 case-audit in the hospital had a positive return on investment caused by a reduced length of stay due to a more appropriate antibiotic therapy. Based on the extensive data analysis, a model of this intervention could be constructed. This model could be used by other institutions, using their own data to estimate the effects of a day 2 case-audit in their hospital.

Original languageEnglish
Article numbere0126106
Number of pages12
JournalPLoS ONE
Volume10
Issue number5
DOIs
Publication statusPublished - 8-May-2015

Keywords

  • ANTIMICROBIAL STEWARDSHIP
  • HEALTH-CARE
  • ECONOMIC OUTCOMES
  • PROGRAM
  • INFECTIONS
  • INTERVENTION
  • PREVENTION
  • GUIDELINES
  • MANAGEMENT
  • RESISTANCE

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