Cost-utility of repeated screening for chlamydia trachomatis

Robin de Vries*, Jan E. A. M. van Bergen, Lolkje T. W. de Jong-van den Berg, Maarten J. Postma, PILOT-CT Study Grp

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)
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Objective: To estimate the cost-effectiveness of repeated screening for chlamydia trachomatis at various time intervals compared to one-off screening of Dutch young adults.

Methods: We used a dynamic model to fully take the spread of the disease over time in the population into account, with data being used gathered within the context of a recently performed pilot study in The Netherlands. The screening frequencies analyzed were: every year, every 2 years, every 5 years, and every 10 years. The strategies were compared in terms of incremental cost-effectiveness, expressed as the net costs per quality-adjusted life-year (QALY).

Results: For all interval strategies, with the exception of screening every year, incremental cost-effectiveness stays below the informal Dutch threshold of 20,000 per QALY.

Conclusions: From a health-economic point of view, for the Dutch situation, we estimated screening every 2 years as the optimal strategy among the options investigated.

Original languageEnglish
Pages (from-to)272-274
Number of pages3
JournalValue in Health
Issue number2
Publication statusPublished - 2008


  • chlamydia trachomatis
  • cost-utility analysis
  • dynamic model
  • screening

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